Search for dissertations about: "stem cell regulation"
Showing result 1 - 5 of 266 swedish dissertations containing the words stem cell regulation.
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1. Novel Insights into Haematopoietic Stem Cell Regulation and Function
Abstract : The haematopoietic stem cell (HSC) is a somatic stem cell essential for life long haematopoiesis; HSCs have the capability to differentiate into all mature types of blood cells and can also undergo self-renewal to maintain their own numbers. They also have the potential to reconstitute a complete haematopoietic system following HSC transplantation, also known as bone marrow transplantation, which is used to treat many haematopoietic disorders. READ MORE
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2. Regulation of Mast Cell Survival
Abstract : Mast cells are long-lived effector cells of importance for both acute and chronic inflammations. Mast cells can be activated in many different ways, leading to the release of inflammatory mediators. In contrast to most other inflammatory cells, activated mast cells have the capacity to recover, regranulate and thereby be activated again. READ MORE
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3. Molecular mechanisms of embryonic stem cell pluripotency: transcription, telomere maintenance and proliferation
Abstract : Somatic cell nuclear transfer and generation of induced pluripotent stem cells provide potential routes towards generation of patient specific embryonic stem (ES) cells. These procedures require induction of Oct4 gene expression, high telomerase activity and specific cell proliferation, characteristics shared with cancer stem cells. READ MORE
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4. Molecular regulation of hematopoietic stem cells
Abstract : Hematopoietic stem cells (HSCs) are ultimately responsible for the all mature blood cell production. They can primarily be found in the bone marrow (BM) at a low frequency (~0.02%). READ MORE
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5. Identification of stem cell factors - Novel protein-protein interactions and their functions
Abstract : Embryonic stem (ES) cells provide an unlimited source of cells potentially useful for regenerative medicine, however, prior to clinical implementation, additional basic research is needed. This thesis is focused upon different molecular aspects regarding ES cells, primarily by finding novel stem cell protein-protein interactions and their functions. READ MORE