Search for dissertations about: "stem cells homing"

Showing result 1 - 5 of 12 swedish dissertations containing the words stem cells homing.

2. 1. Regulation of Hematopoietic Stem and Progenitor Cells by Bone Marrow Niche Components

   Author : Hong Qian; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cell; Hematologi; extracellular fluids; Haematology; bone marrow; Hematopoiesis; extracellulära vätskor;

   Abstract : Throughout the lifespan of an individual, enormous numbers of mature blood cells are generated by hematopoietic stem cells (HSCs) in the bone marrow (BM). The HSC is a cell that can self-renew to maintain the HSC pool and differentiate into all types of mature blood cells. READ MORE

4. 2. Mesoporous Implants for Localized Controlled Drug Delivery

   Author : Johan Karlsson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; release kinetics; mesoporous titania; biomineralization; drug delivery; Biomedical implants; osseointegration; osteoporosis drugs; nanotopography; stem cells homing;

   Abstract : The use of bone-anchored implants is today a routine treatment for patients with normal regenerative capacity. However, there is an ongoing development within implant research to improve the osseointegration of implants. READ MORE

5. 3. Therapeutic potential of natural killer cells in multiple myeloma

   Author : Evren Alici; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Natural Killer cells; immunotherapy; multiple myeloma; gene therapy;

   Abstract : Multiple Myeloma (MM) is an incurable plasma cell neoplasm with a median length of survival after diagnosis of approximately three years; therefore new treatment modalities to eradicate the disease are needed. Although the disease remains incurable, current main alternatives are drug treatment modalities and autologous stem cell transplantation (ASCT). READ MORE

6. 4. Experimental studies of human fetal liver cells : in regard to in utero hematopoietic stem cell transplantation

   Author : Bim Lindton; Karolinska Institutet; Karolinska Institutet; []
   Keywords : In utero transplantation; fetal liver cells; mixed lymphocyte culture; CD3; CD56; HLA class II; parvovirus B 19 capsids; corticosteroids; cytotoxic drugs; colony formation.;

   Abstract : Successful in utero hematopoietic stem cell transplantation represents a potential step forward in the management of patients with severe inherited hematological, metabolic and immunological disorders. Animal data from a number of species have demonstrated evidence of engraftment, but to date the only effective in utero transplantations (IUTx) in humans have been performed in fetuses with severe immunodeficiencies, suggesting that the fetal immune system play a vital role in the success or failure of in utero transplantation. READ MORE

7. 5. Targeted therapeutic strategies for prostate cancer treatment using novel lipid kinase inhibitors in combination with current drugs

   Author : Julius Semenas; Jenny L. Persson; Anna Berghard; Maria Fällman; Thomas Grundström; Lukas Kenner; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; bone metastasis; castration-resistant; treatment; precision therapy; PIP5K1A; steroid hormone receptors; cancer stem cells; Oncology; onkologi;

   Abstract : Prostate cancer (PCa) is one of the most common cancer types and the fifth cancer-related cause of death among Western world men.  The sex steroid hormone, androgen and androgen receptor (AR) play important roles in PCa progression. READ MORE