Search for dissertations about: "structural model"
Showing result 1 - 5 of 1744 swedish dissertations containing the words structural model.
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1. Quantifying Structural Change : A Model Based Approach
Abstract : .... READ MORE
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2. Improved pharmacometric model building techniques
Abstract : Pharmacometric modelling is an increasingly used method for analysing the outcome from clinical trials in drug development. The model building process is complex and involves testing, evaluating and diagnosing a range of plausible models aiming to make an adequate inference from the observed data and predictions for future studies and therapy. READ MORE
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3. Transthyretin and the transthyretin-related protein: A structural study
Abstract : Transthyretin (TTR) is one of several proteins involved in amyloid disease in humans. Unknown conformational changes of the native state of TTR result in aggregation of TTR molecules into amyloid fibrils, which accumulate in extracellular tissues. This may result in different clinical symptoms, e.g. READ MORE
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4. Stochastic model updating and model selection with application to structural dynamics
Abstract : Uncertainty induced by our incomplete state of knowledge about engineering systems and their surrounding environment give rise to challenging problems in the process of building predictive models for the system behavior. One such challenge is the model selection problem, which arises due to the existence of invariably multiple candidate models with different mathematical forms to represent the system behavior, and so there is a need to assess their plausibility based on experimental data. READ MORE
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5. Membrane Protein Tailoring and Structural Studies of Leukotriene C4 Synthase
Abstract : Despite a dramatic increase in the number of proteins that have been structurally characterized in recent years, there are still less than 200 unique structures of membrane proteins known today. This is only 1% of the total number of unique protein structures found in structural databases worldwide. READ MORE