Search for dissertations about: "structure determination"

Showing result 21 - 25 of 405 swedish dissertations containing the words structure determination.

2. 21. Structure determination and thermodynamic stabilization of an engineered protein-protein complex

   Author : Elisabet Wahlberg; Per-Åke Nygren; Bengt-Harald Jonsson; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; protein structure; coupled folding; NMR spectroscopy; protein stability; protein-protein interactions; binding thermodynamics; isothermal titration calorimetry; protein engineering; Structural biochemistry; Strukturbiokemi;

   Abstract : The interaction between two 6 kDa proteins has been investigated. The studied complex of micromolar affinity (Kd) consists of the Z domain derived from staphylococcal protein A and the related protein ZSPA-1, belonging to a group of binding proteins denoted affibody molecules generated via combinatorial engineering of the Z domain. READ MORE

4. 22. Structure and Dynamics of the Hepatitis B Virus Encapsidation Signal Revealed by NMR Spectroscopy

   Author : Sara Flodell; Stephan Grzesiek; Umeå universitet; []
   Keywords : HBV; RNA; isotope labelling; NMR; structure determination; medicinsk biokemi; Medical Biochemistry;

   Abstract : This thesis describes the study of the three-dimensional structure and dynamics of the hepatitis B virus (HBV) encapsidation signal, epsilon, by means of nuclear magnetic resonance (NMR) and mutational data. HBV replicates by reverse transcription of an RNA pregenome into the viral DNA genome, which becomes enclosed in viral particles (encapsidation). READ MORE

5. 23. Identification and characterisation of chitin and cellulose synthases in oomycetes : New tools for biochemical studies and structure determination

   Author : Stefan Klinter; Vincent Bulone; Lauren S. McKee; Mirjam Czjzek; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biochemical characterisation; cellulose synthase; chitin synthase; in vitro activity assay; microtubule-interacting and trafficking domain; nanoparticle; oomycetes; phylogenetic analysis; yeast engineering; biokemisk karakterisering; cellulosasyntas; kitinsyntas; in vitro aktivitetsanalys; mikrotubulus-interagerande och -trafikerande domän; nanopartikel; oomyceter; fylogenetisk analys; jäst proteinteknik; Bioteknologi; Biotechnology;

   Abstract : Despite resembling ‘true’ fungi in terms of morphological features, oo­mycetes form a distinct eukaryotic lineage of filamentous microorganisms that belongs to the stramenopiles, a group of protists also comprising the closely-related brown algae and diatoms. Many oomycetes are devastating pathogens of plants and animals, globally causing significant economic los­ses in the agriculture and aquaculture industries, and posing considerable environmental damage to natural ecosystems. READ MORE

6. 24. Metallicity determination of M dwarfs

   Author : Sara Lindgren; Ulrike Heiter; Ansgar Reiners; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; stars: low mass - stars: abundances; fundamental parameters - technique: spectroscopic; photometric - planets and satellites: formation;

   Abstract : M dwarfs constitute around 70% of all stars in the local Galaxy. Their multitude together with their long main-sequence lifetimes make them important for studies of global properties of the Galaxy such as the initial mass function or the structure and kinematics of stellar populations. READ MORE

7. 25. Design of new materials with crystal structure-related properties : The role of lone pair cations

   Author : Eleni Mitoudi Vagourdi; Mats Johnsson; Vadim Kessler; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Crystal structure determination; New oxohalide compounds; Lone-pair electrons; X-ray diffraction; Physical properties; Inorganic Chemistry; oorganisk kemi;

   Abstract : Non-centrosymmetry and low-dimensional arrangements, e.g. chains or layers, are very attractive structural characteristics of crystalline compounds since they are linked to some physical properties including nonlinear optical activity, ferroelectricity and magnetic frustration. READ MORE