Search for dissertations about: "study of colorectal carcinoma"

Showing result 1 - 5 of 28 swedish dissertations containing the words study of colorectal carcinoma.

  2. 1. Cell adhesion proteins in different invasive patterns of colon carcinomas : a morphometric and molecular genetic study

    Author : Victoria Hahn-Strömberg; Lennart Franzén; Richard Palmqvist; Örebro universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; colon carcinoma; growth pattern; tight junction; Complexity Index; cell adhesion; E-cadherin; Beta-catenin; Occludin; Claudin.; Medicine; Medicin; Biomedicin; Biomedicine;

    Abstract : Colorectal carcinoma is the second most common type of cancer in both men and women in Sweden. Cancer of the colon and rectum are often considered together and their ten year survival rate is approximately 50 – 60 % depending on sex and location. READ MORE

  4. 2. Cancer of unknown primary: searching for the etiological clues. A population-based epidemiological study in Sweden

    Author : Xiaochen Shu; Allmänmedicin och klinisk epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer of unknown primary; causes of death; familial risk; immigrant; incidence; multiple malignancies; risk factor; squamous cell carcinoma; standardizedincidence ratio; survival;

    Abstract : This thesis aimed to search for etiological clues about cancer of unknown primary(CUP) by gathering novel information. The Swedish national registries were used and CUP cases were identified according to the seventh revision of the International Classification of Diseases. READ MORE

  5. 3. Immunotherapy with the anti-EpCAM monoclonal antibody and cytokines in patients with colorectal cancer : a clinical and experimental study

    Author : Maria Gustafsson Liljefors; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Colorectal carcinoma; monoclonal antibodies; GM-CSF; pharmacokinetics; prognosis; bone marrow micrometastases; cytokeratin-positive cells; Colorectal carcinoma;

    Abstract : The tumor-associated antigen EpCAM (epithelial cell-adhesion molecule) (C017-1A) is over expressed by various human carcinomas, including colorectal carcinoma (CRC). This antigen can be used as a target structure for specific immunotherapy with vaccines and monoclonal antibodies (MAb). READ MORE

  6. 4. Mismatch repair deficiency in colorectal cancer : prognosis and prediction for basic treatment strategies

    Author : Ioannis Gkekas; Jan Novotny; Karin Strigård; Richard Palmqvist; Ulf Gunnarsson; Christian Sturesson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; defective mismatch repair; prognosis and prediction; Oncology; onkologi;

    Abstract : Colorectal cancer (CRC) remains a significant healthcare problem worldwide, being the third most common cancer and the fourth most frequent cause of cancer death. Environmental and dietary factors such as alcohol abuse, cigarette smoking, and genetic predisposition seem to constitute the main aetiologies. READ MORE

  7. 5. Monoclonal antibodies and cytokines for therapy of patients with advanced colorectal carcinoma : a clinical and immunological study

    Author : Anna-Lena Hjelm Skog; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Colorectal carcinoma; Monoclonal antibodies; IL-2; IFN-[alpha]; GM-CSF; cytokine antibodies; neopterin; sIL-2R; immune suppression;

    Abstract : There is a great need for developing and improving treatment alternatives in colorectal carcinoma (CRC). The tumour associated antigen (TAA) GA733/CO17-1A is expressed by more than 90% of all CRCs, on the majority of both primary and metastatic CRC cells. READ MORE