Search for dissertations about: "substance"

Showing result 1 - 5 of 695 swedish dissertations containing the word substance.

2. 1. Substance use in adolescents and young adults: Interactions of drugs of abuse and the role of parents and peers in early onset of substance use

   Author : Jonas Berge; Lund Psykiatri; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Substance use; Alcohol; Tobacco; Cannabis; Illicit drugs; Adolescents; Young adults;

   Abstract : Background: Misuse of substances is a major contributor to disability and mortality worldwide. The use of tobacco, alcohol, and illegal drugs in adolescence and young adulthood are well-known risk factors for subsequent substance-related harms. READ MORE

4. 2. Substance P Endopeptidase : Purification and Characterizataion of Enzyme Activity and Evaluation of its Function during Stressful Condition

   Author : Krister Karlsson; Lars Oreland; Fred Nyberg; Tsukasa Sakurada; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Substance P Endopeptidase; Neuropeptide; Central Nervous System; Purification; Drug Dependence; Heat Stress; Farmakologi; Pharmacological research; Farmakologisk forskning;

   Abstract : The purification and biochemical characterization of the substance P (SP) hydrolyzing enzyme, substance P endopeptidase (SPE), have been carried out; with subsequent orientation in neurobiological fundamental processes involved in opioid dependence, withdrawal, and heat-stress.SPE was purified from rat spinal cord, human spinal cord and cerebrospinal fluid (CSF), rat ventral tegemental area (VTA), and rat hippocampus. READ MORE

5. 3. Use and misuse of sedative drugs and related substances - Findings in the general population and in individuals with opioid dependence

   Author : Tove Abrahamsson; Lund Psykiatri; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Substance use; Sedatives; Anxiolytics; Hypnotics; Prescription drug miuse; Benzodiazepines; Z-drugs; Pregabalin; Self-assessed health; Quality of life; Opioid dependence; Opiate maintenance treatment; Mortality;

   Abstract : Background: Prescription sedatives are efficient in the treatment of anxiety and sleeping disorders, but are associated with a risk of misuse and dependence, as well as an increased risk of accidents, injuries and overdoses, both in the general population and especially in individuals with other substance misuse. The present thesis aims to investigate prescription sedative use and misuse in two kinds of samples - in the general population, with focus on its association with subjective health and quality life, and in the subpopulation of individuals with opioid dependence, with focus on treatment outcome in opioid maintenance treatment and mortality. READ MORE

6. 4. Substance Use and Violence : Influence of Alcohol, Illicit Drugs and Anabolic Androgenic Steroids on Violent Crime and Self-directed Violence

   Author : Lena Lundholm; Ingemar Thiblin; Ulrika Haggård; Claudia Fahlke; Johan Hallqvist; Tom Palmstierna; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Substance abuse; violent crime; violent suicide; anabolic androgenic steroids;

   Abstract : Interpersonal violence and suicide are major health concerns, leading to premature death, extensive human suffering and staggering monetary costs. Although violent behaviour has multiple causes, it is well known that acute substance intake and abuse increase the risks of both interpersonal and self-directed violence. READ MORE

7. 5. Alcohol and aging : a multimethod study on heterogeneity and multidimensionality

   Author : Wossenseged Birhane Jemberie; Mojgan Padyab; Fredrik Snellman; Malin Eriksson; Neda Agahi; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; older adults; substance use disorder; alcohol use disorder; comorbidity; recovery; alcohol treatment; aging; healthy aging; integrated care; person-centered care; biopsychosocial model; register-based; longitudinal; latent class; medical behavioral science; medicinsk beteendevetenskap; health services research; hälso- och sjukvårdsforskning; health services research; hälso- och sjukvårdsforskning; psykiatri; Psychiatry;

   Abstract : Background and Objectives: With an ageing population, the number of older persons with substance use problems, particularly problematic alcohol use, is increasing. Despite grow­ing recognition of the negative consequences of problematic alcohol use on older persons, there is a dearth of knowledge about the alcohol use profiles and the dimensionality of alcohol problems in older people. READ MORE