Search for dissertations about: "superoxide dismutase"

Showing result 1 - 5 of 73 swedish dissertations containing the words superoxide dismutase.

  2. 1. Superoxide dismutase : radiobiological significance : occurrence in human tissues, tumours and tumour cell-lines

    Author : Gunnar Westman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Superoxide dismutase; Radiation sensitivity; Diethyldithiocarbamate; Haemolysis; Catalase; Glutathione Peroxidase; Potential lethal damage;

    Abstract : .... READ MORE

  4. 2. Superoxide dismutase 1 and cataract

    Author : Eva Olofsson; Anders Behndig; Stefan Marklund; Marjorie Lou; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cataract; diabetes mellitus; nitric oxide; superoxide; superoxide dismutase; SOD1 null mice; Ophtalmiatrics; Oftalmiatrik; oftalmiatrik; Ophtalmology;

    Abstract : Light and oxygen generate harmful reactive oxygen species (ROS) in the lens, causing biochemical changes that gradually disarrange the lens fibres resulting in light scattering and loss of transparency. In the healthy eye, this chronic exposure to oxidative stress may lead to age-related cataract. READ MORE

  5. 3. Protein folding studies of human superoxide dismutase and ALS associated mutants

    Author : Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. READ MORE

  6. 4. From Time-Averaged to Time-Resolved Crystallography: Studies on Superoxide Dismutase and Myoglobin

    Author : Thomas Ursby; Lunds universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; superoxide dismutase; Bayesian statistics; electron difference maps; synchrotron; docking site; photolysis; myoglobin; Time-resolved crystallography; Laue; thermostability; Sulfolobus solfataricus; Molecular biophysics; Molekylär biofysik;

    Abstract : We have studied protein motions with nanosecond time-resolved crystallography. The release of carbon monoxide from its complex with myoglobin (MbCO) was triggered by nanosecond laser pulses. X-ray data were collected with time delays ranging from 4 ns to 1.9 ms using the Laue method, at the European Synchrotron Radiation Facility in Grenoble. READ MORE

  7. 5. Protein Engineering of Extracellular Superoxide Dismutase : Characterization of Binding to Heparin and Cellular Surfaces

    Author : Ing-Marie Ahl; Lena Tibell; Bengt-Harald Jonsson; Steen Vang Petersen; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : Accumulating evidence indicates that oxygen free radicals are involved in many diseases and pathological conditions, such as aging, inflammation, reperfusion damage of ischemic tissue and various cardiovascular diseases. Extracellular superoxide dismutase (ECSOD) thus plays a major role in the maintenance of cells by providing protection against these toxic substances in the extracellular space. READ MORE