Search for dissertations about: "supported phospholipid bilayer"

Showing result 1 - 5 of 15 swedish dissertations containing the words supported phospholipid bilayer.

  2. 1. Interaction Between Antimicrobial Peptides and Phospholipid Membranes : Effects of Peptide Length and Composition

    Author : Lovisa Ringstad; Martin Malmsten; Per Hansson; Jeremy Ramsden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adsorption; antibacterial; antimicrobial peptide; bilayer; ellipsometry; electrochemistry; electrostatic interactions; hydrophobicity; liposome; membrane; monolayer; phospholipid; secondary structure; supported bilayer.; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : Due to increasing problems with bacterial resistance development, there is a growing need for identifying new types of antibiotics. Antimicrobial peptides constitute an interesting group of substances for this purpose, since they are believed to act mainly by disrupting the bacterial membrane, which is a fast and non-specific mechanism. READ MORE

  4. 2. Antimicrobial Peptide Interactions with Phospholipid Membranes : Effects of Peptide and Lipid Composition on Membrane Adsorption and Disruption

    Author : Adam A Strömstedt; Martin Malmsten; Georges Belfort; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; peptide; adsorption; liposome; membrane; melittin; cholesterol; tryptophan; phospholipid; bilayer; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : The interactions between antimicrobial peptides and phospholipid membranes were investigated, in terms of lipid headgroup variations and the role of cholesterol, as well as peptide composition and structure. Also strategies for increasing proteolytic stability were evaluated. READ MORE

  5. 3. On the Formation of Supported Phospholipid Bilayers

    Author : Erik Reimhult; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; vesicle adsorption; formation kinetics; SPR; QCM-D; SPB; AFM; supported lipid bilayer; supported membrane; liposome;

    Abstract : Lipid bilayers are a central component of both the structure and function of biological membranes, like the one surrounding cells of living organisms. Since the lipid bilayer provides a host matrix for membrane proteins, which perform many of the specialized tasks in cells like energy, signal and material transduction, researchers have tried to develop artificial model membranes to study a variety of membrane protein functions. READ MORE

  6. 4. Supported phospholipid bilayer-based surface modifications for controlling cells at surfaces

    Author : Dorota Dahlborg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cell attachment; QCM-D; neural cells; supported phospholipid bilayer; peptide; cell-surface interaction; surface functionalization; stem cells; IKVAV; cell differentiation;

    Abstract : .... READ MORE

  7. 5. Grazing incidence small angle neutron scattering as a tool to study curved biomembranes on nanostructured surfaces

    Author : Karolina Mothander; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GISANS; Reflectometry; Neutron scattering; Phospholipid; supported lipid bilayer; Nanowires; confocal microscopy; QCM-D;

    Abstract : Curvature in lipid-based biomembranes provides compartmentalization in cells and can act as regulator of biological activity in living systems. The study of these biomembranes require novel model systems and new methods. In this work I have used a supported phospholipid bilayer on a hexagonal array of silicon nanowires. READ MORE