Search for dissertations about: "suppressor"
Showing result 1 - 5 of 484 swedish dissertations containing the word suppressor.
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1. Neutrophils as Suppressor Cells and their role in Multiple Myeloma
Abstract : .... READ MORE
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2. Functional Characterization of the Yeast Tumour Suppressor Homologue Sro7p
Abstract : Correct targeting of newly synthesized proteins to appropriate domains of the cell membrane is crucial to cellular architecture, polarity and function, making it no surprise that many proteins of the secretory machinery are conserved throughout evolution. This work presents a functional characterisation of the Saccharomyces cerevisiae cell polarity protein and tumour suppressor homologue, Sro7p. READ MORE
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3. Cellular, Molecular and Functional Characterization of the Tumor Suppressor Candidate MYO1C
Abstract : Tumor suppressor genes play a role as a growth regulator and a gatekeeper of a cell. Their inactivation is often detected in malignant tumors. Identification of novel tumor suppressor gene candidates may help to further understand tumorigenesis and aid in the discovery of a new treatment leading toward cure of cancer. READ MORE
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4. On the role of the retinoblastoma tumor suppressor gene in hematopoietic differentiation
Abstract : The aim of this study was to investigate the role of some tumor suppressor gene products (with emphasis on the retinoblastoma suppressor gene product) in the regulation of differentiation and proliferation in leukemic and normal hematopoietic cells. For this purpose, the expression of the tumor suppressor genes RB, p53 and p16 were artificially altered. READ MORE
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5. On the Role of the Tumor Suppressor p53 in Leukemic Cell Differentiation
Abstract : Leukemic cells suffer from an impaired ability to differentiate due to inherited or acquired genetic lesions. These genetic changes can sometimes be bypassed with various compounds both in vitro, and, more rarely, in vivo, thus inducing terminal differentiation of the leukemic cells. READ MORE