Search for dissertations about: "surface proteins"

Showing result 21 - 25 of 983 swedish dissertations containing the words surface proteins.

  2. 21. Tailormade Surfaces for Extended CE Applications

    Author : Sara Ullsten; Karin Markides; Staffan Folestad; Gerhardus J de Jong; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; capillary electrophoresis; mass spectrometry; surface properties; coatings; polymers; liposomes; proteins; drugs; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Abstract : The combination of capillary electrophoresis (CE) and mass spectrometry (MS) constitutes a powerful microanalytical system in the fields of biology, medicine and chemistry. This thesis describes the development of three novel capillary coatings and demonstrates how these extend the utility of CE as a high-efficiency separation technique in protein analysis and biopharmaceutical drug screening. READ MORE

  4. 22. Dangerous Proteins and Where to Find Them- Structural and functional studies of bacterial and viral proteins interacting with human immune receptors in health and disease

    Author : Sibel Uzuncayir; Medicinsk strukturbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; immunology; structural biology;

    Abstract : Bacteria and viruses are threats to human that evolved strategies to bypass the immune system and can cause massive damage. Understanding these strategies and elucidating pathogen interacting partners within the human immune system will pave the way for discovery of new medicines and increase human well-being. READ MORE

  5. 23. Surface expression using the AIDA autotransporter : Towards live vaccines and whole-cell biocatalysis

    Author : Martin Gustavsson; Gen Larsson; Per Berglund; Andres Veide; Jan-Willem de Gier; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; AIDA-autotransporter; Escherichia coli; live vaccines; surface expression;

    Abstract : The area of surface expression has gathered a lot of interest from research groups all over the world and much work is performed in the area. Autotransporters have been used for surface expression in Gram-negative bacteria. READ MORE

  6. 24. Macromolecules at Interfaces

    Author : Helén Larsericsdotter; Sven Oscarsson; Jos Buijs; Willem Norde; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Protein; Adsorption; Immobilization; Surface; Surface Plasmon Resonance; SPR; Mass Spectrometry; MS; Differential Scanning Calorimetry; DSC; FT ICR; Lysozyme; Bovine Serum Albumin; BSA; Myoglobin; Globular; Kemi; Chemistry; Kemi;

    Abstract : In this thesis, the structure and stability of globular proteins adsorbed onto nanometer-sized hydrophilic silica particles were investigated using differential scanning calorimetry (DSC), hydrogen/deuterium exchange (HDX), and mass spectrometry (MS). The adsorption process itself was characterized with fluorescence and absorption spectroscopy and surface plasmon resonance (SPR). READ MORE

  7. 25. Novel Functionalized Nanopores for Plasmonic Sensing

    Author : Bita Malekian; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; extinction spectra; nanopores; proteins; nanocaves; nanowells; surface plasmon resonance; nuclear pore complex; colloidal lithography; nanoplasmonic sensor; label-free sensing; electron beam lithography; plasmonic nanostructures;

    Abstract : Nanoplasmonic sensors offer a label-free platform for real-time monitoring of biomolecular interactions by tracking changes in refractive index through optical spectroscopy. However, other surface sensitive techniques such as conventional surface plasmon resonance offer similar capabilities with equal or even better resolution in terms of surface coverage. READ MORE