Search for dissertations about: "synthesis of monosaccharide"

Showing result 1 - 5 of 9 swedish dissertations containing the words synthesis of monosaccharide.

  2. 1. Exploring the structure of oligo- and polysaccharides : Synthesis and NMR spectroscopy studies

    Author : Hanna Jonsson; Göran Widmalm; Antonio Molinaro; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; NMR spectroscopy; synthesis; lipopolysaccharides; conformational studies; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : A deeper understanding of the diversity of carbohydrates and the many applications of oligo- and polysaccharides found in nature are of high interest. Many of the processes involving carbohydrates affect our everyday life. This thesis is based on six papers all contributing to an extended perspective of carbohydrate property and functionality. READ MORE

  4. 2. Synthetic analogs of sialyl Lewis x

    Author : Ulf Ellervik; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; stereoselective synthesis; regioselective synthesis; lactam analogs; lactone; Selectin; Sialyl Lewis x; SLex; Organic chemistry; Organisk kemi;

    Abstract : The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. READ MORE

  5. 3. Glycoconjugates : Solid-phase synthesis and biological applications

    Author : Fredrik Wallner; Mikael Elofsson; Jan Kihlberg; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glycoconjugate; Glycolipid; Solid-phase synthesis; Glycosylation; Gel-phase 19F-NMR spectroscopy; Fluorinated linker; Carbohydrat array; CD1; Organic chemistry; Organisk kemi;

    Abstract : Glycoconjugates are biologically important molecules with diverse functions. They consist of carbohydrates of varying size and complexity, attached to a non-sugar moiety as a lipid or a protein. Glycoconjugate structures are often very complex and their intricate biosynthetic pathways makes overexpression difficult. READ MORE

  6. 4. Synthesis of oligosaccharides for structural, conformational and molecular recognition investigations

    Author : Peter Söderman; Inge Lundt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Abstract : Carbohydrates are involved cell-cell interaction. Synthesis of small and medium sized oligosaccharides is important to gain more understanding about the their physical properties that are crucial for their action in molecular recognition events. READ MORE

  7. 5. Molecular basis for galectin-ligand interactions : Design, synthesis and analysis of ligands

    Author : Kristoffer Peterson; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Galectin; Structure-based design; Thiodigalactoside; Huisgen 1; 3-dipolar cycloaddition; Protein-ligand binding interactions;

    Abstract : Galectins are a class of β-galactoside-binding proteins that bind glycoconjugates and have been implicated in cancer, regulation of immunity and inflammation. Design and synthesis have achieved highly potent and selective galectin ligands that can inhibit interactions with glycoproteins and have consequent cellular effects. READ MORE