Search for dissertations about: "t memory cells markers"

Showing result 1 - 5 of 33 swedish dissertations containing the words t memory cells markers.

2. 1. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease

   Author : Andrea Tompa; Maria Faresjö; Karin Åkesson; Mikael Karlsson; Jönköping University; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; celiac disease; children; biomarkers; immune markers; flow cytometry; cryopreservation; T cells; T-regulatory cells; B cells; B-regulatory cells; cytokines; chemokines; acute phase proteins; adipocytokines; matrix metalloproteinases;

   Abstract : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. READ MORE

4. 2. CD19-targeting CAR T Cells for Treatment of B Cell Malignancies : From Bench to Bedside

   Author : Hannah Karlsson; Angelica Loskog; Karl-Johan Malmberg; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; chimeric antigen receptors; CAR T cells; T cell therapy; immunotherapy; CD19; Bcl-2 family inhibitors; B cell malignancies; Klinisk immunologi; Clinical Immunology;

   Abstract : Immunotherapy for cancer is a young research field progressing at high speed. The first chimera of an antibody and a signaling chain was designed by Zelig Eshhar and was later further developed to enhance existing T cell therapy by combining a single-chain fragment of an antibody with the CD3 zeta chain of the TCR complex. READ MORE

5. 3. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

   Author : Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

   Abstract : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. READ MORE

6. 4. Commensal microbes, immune reactivity and childhood inflammatory bowel disease

   Author : Cecilia Barkman; Göteborgs universitet; []
   Keywords : Inflammatory bowel disease; IBD; Pediatric; Childhood; Microbiota; T cells; B cells; cytokine; IL-12; monocytes; phagocytosis; intracellular signaling pathway; Crohn s disease; ulcerative colitis; children; flora;

   Abstract : Inflammatory bowel disease (IBD) is characterized by chronic and relapsing intestinal inflammation of unknown etiology, but immune activation by the commensal microbiota probably plays a major role. The two major categories of IBD are ulcerative colitis and Crohn’s disease. READ MORE

7. 5. B cell fate following immunization : from memory B cells to plasma cells

   Author : Paola Martínez Murillo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Most approved successful human vaccines induce neutralizing antibody titers maintained above a given threshold for long-term protection against potential pathogen exposure. The pathogens targeted by these vaccines are antigenically stable and the relevant epitopes are immunogenic. READ MORE