Search for dissertations about: "tandem mass spectrometry"

Showing result 1 - 5 of 85 swedish dissertations containing the words tandem mass spectrometry.

  1. 1. Improved Neuropeptide Identification Bioinformatics and Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Maria Fälth Savitski; Uppsala universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; neuropepides; database; peptide identification; peptide fragmentation; mass spectrometry; tandem mass spectromerty; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik;

    Abstract : Bioinformatic methods were developed for improved identification of endogenous peptides using mass spectrometry. As a framework for these methods, a database for endogenous peptides, SwePep, was created. It was designed for storing information about endogenous peptides including tandem mass spectra. READ MORE

  2. 2. Liquid Chromatography Coupled to Mass Spectrometry Implementation of Chemometric Optimization and Selected Applications

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : My Moberg; Uppsala universitet.; [2006]
    Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

    Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

  3. 3. Metabolic Studies with Liquid Separation Coupled to Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Allard; Uppsala universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; liquid chromatography; mass spectrometry; tandem mass spectrometry; method development; capillary electrophoresis; electrospray ionization; time-of-flight; quantitation; metabolomics; metabonomics; pattern recognition; ximelagatran; melagatran; charge state; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : Metabolism is the sum of all chemical processes with the purpose to maintain life, as well as enable reproduction, in a living organism. Through the study of metabolism, increased understanding of pharmacological mechanisms and diseases can be achieved. READ MORE

  4. 4. Secondary and Higher Order Structural Characterization of Peptides and Proteins by Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Christopher Adams; Uppsala universitet.; [2007]
    Keywords : Engineering physics; Protein Structure; Mass Spectrometry; Electron Capture Dissociation; Tandem Mass Spectrometry; Teknisk fysik;

    Abstract : The work in this thesis has demonstrated the advantages and limitations of using MS based technologies in protein and peptide structural studies. Tandem MS, specifically electron capture dissociation (ECD) have shown the ability to provide structural insights in molecules containing the slightest of all modifications (D-AA substitution). READ MORE

  5. 5. Organic Phosphorus Compounds in Aquatic Sediments Towards Molecular Identification with Mass Spectrometry

    University dissertation from Uppsala : Universitetsbiblioteket

    Author : Heidi De Brabandere; Uppsala universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; electrospray ionisation; mass spectrometry; liquid chromatography; organic phosphorus; aquatic sediment; eutrophication; sample preparation; extraction; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Abstract : Phosphorus (P) regulates trophic status in most aquatic systems. However, only bioavailable P contributes to primary production. In most lakes and shallow seas, mineralisation of sediment P into its bioavailable form and its release to the water column is important for maintaining primary production. READ MORE