Search for dissertations about: "tandem mass spectrometry"

Showing result 11 - 15 of 133 swedish dissertations containing the words tandem mass spectrometry.

  2. 11. Investigation of Modified Cellulose and Starch via Hydrolysis and Mass Spectrometry

    Author : Arieh Cohen; Avdelningen för arbets- och miljömedicin; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ESI-MS; Polysaccharides; Hydrolysis; Cellulases; Starch Hydrolases; Enzymatic Degradation; Enzymes; Substituent Distribution; Modified Cellulose; Mass Spectrometry; Modified Starch; Analytical chemistry; Analytisk kemi; HPAEC-PAD;

    Abstract : Starches and celluloses can be chemically modified in order to affect their physiochemical properties. Modification of these carbohydrate polymers entails derivatising their free hydroxyl groups with functional groups. READ MORE

  4. 12. Chemical Derivatization in Combination with Liquid Chromatography Tandem Mass Spectrometry for Detection and Structural Investigation of Glucuronides

    Author : Matilda Lampinen Salomonsson; Mikael Hedeland; Ulf Bondesson; Calle Nilsson; Uppsala universitet; []
    Keywords : Pharmaceutical chemistry; Derivatization; mass spectrometry; glucuronide; drug metabolism; increased sensitivity; structural investigation; 2-chloro-1-methylpyridinium iodide CMPI ; 1-ethyl-3- 3-dimethylaminopropyl -carbodiimide EDC ; 2-picolylamine PA ; 1; 2-dimethylimidazole-4-sulfonyl chloride DMISC ; Farmaceutisk kemi;

    Abstract : This thesis presents novel approaches for structural investigation of glucuronides using chemical derivatization in combination with liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MSn).Today, LC-ESI-MSn is the dominant technique for quantitative as well as qualitative analyses of metabolites, due to its high sensitivity and selectivity. READ MORE

  5. 13. High Rate Electron Capture Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    Author : Youri Tsybin; Per Håkansson; Ron M.A. Heeren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physics; mass spectrometry; Fourier transform ion cyclotron resonance; peptides and proteins; ion-electron interaction; electron capture dissociation; infrared multiphoton dissociation; liquid chromatography; capillary electrophoresis; Fysik; Physics; Fysik;

    Abstract : Advances in science and technology during the past decade have greatly enhanced the level of the structural investigation of macromolecules – peptides and proteins. Biological mass spectrometry has become one of the most precise and sensitive techniques in peptide and protein analysis. READ MORE

  6. 14. Mass spectrometric studies of cellulose ethers

    Author : Dane Momcilovic; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polymerteknik; biopolymers; Polymer technology; Analytisk kemi; Analytical chemistry; enzymatic depolymerisation; reductive amination; electrospray ionisation; cellulose ethers; MALDI; mass spectrometry;

    Abstract : Cellulose based derivatives, such as cellulose ethers, today find many applications in a diverse range of fields. The numerous applications put high demands on the technological performance of the cellulose ethers. READ MORE

  7. 15. A qualitative and quantitative study of nitrotyrosine using mass spectrometry and immunochemistry

    Author : Ann-Sofi Söderling; Göteborgs universitet; []
    Keywords : mass spectrometry; oxidative stress; nitrotyrosine; nitric oxide; protein modification;

    Abstract : Background: Reactive oxygen (ROS), and nitrogen (RNS) species are formed during normal metabolism and in higher concentration in pathological conditions. They may cause cellular damage when the antioxidant defence is unable to balance the production of oxidants. READ MORE