Search for dissertations about: "tandem mass spectrometry"

Showing result 21 - 25 of 133 swedish dissertations containing the words tandem mass spectrometry.

  2. 21. Development and application of alternative methods for profiling proteins N-glycosylation

    Author : Alessandro Quaranta; Leopold Ilag; Niclas Karlsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; N-glycosylation; Glycomics; Glycosylation Biomarkers; Intact Glycoproteins; Glycoform Quantification; Mass Spectrometry; Ion Mobility Spectrometry; MALDI-MS; Paper Spray Ionization; Microfluidics; Magnetic Beads; Immunoaffinity Purification; Nanobodies; Analytical Chemistry; analytisk kemi;

    Abstract : Glycosylation is a post-translational modification (PTM) that exerts profound structural and functional effects on the modified protein. Glycan synthesis and conjugation to proteins are regulated by a myriad of factors, both genetic and environmental, and are also influenced by external stressors. READ MORE

  4. 22. Capillary electroseparations with mass spectrometric detection Nanoparticle-based continuous full filling and applications for complex sample matrices

    Author : Peter Viberg; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytisk kemi; Analytical chemistry; phthalates; continuous full filling; heterocyclic aromatic amines; pseudostationary phase; capillary electrophoresis; electrokinetic chromatography; capillary electrochromatography; nanoelectrospray; mass spectrometry;

    Abstract : One of the major challenges in analytical chemistry is to find techniques and methods for determinations of low abundance compounds in complex sample matrices. This thesis describes the development of new miniaturised analytical techniques comprising capillary electroseparation combined with mass spectrometric detection. READ MORE

  5. 23. Determination of mercury chemical speciation in the presence of low molecular mass thiols and its importance for mercury methylation

    Author : Van Liem-Nguyen; Erik Björn; Ulf Skyllberg; Cynthia Gilmour; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mercury; methylmercury; LMM thiol; mass spectrometry; biogeochemistry; soil; sediment; ICP; WinSGW; modeling; S XANES; ligand exchange; stability constant; boreal wetlands; analytisk kemi; Analytical Chemistry; Environmental Science; miljövetenskap;

    Abstract : Methylmercury (MeHg) is a neurotoxic compound that threatens the well-being of humans and wildlife. It is formed through the methylation of inorganic mercury (HgII) under suboxic/anoxic conditions in soils, sediment and waters. READ MORE

  6. 24. Statistical and machine learning methods to analyze large-scale mass spectrometry data

    Author : Matthew The; Lukas Käll; Fredrik Levander; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry - LC-MS MS; statistical analysis; data processing and analysis; protein inference; large-scale studies; simulation; Bioteknologi; Biotechnology;

    Abstract : As in many other fields, biology is faced with enormous amounts ofdata that contains valuable information that is yet to be extracted. The field of proteomics, the study of proteins, has the luxury of having large repositories containing data from tandem mass-spectrometry experiments, readily accessible for everyone who is interested. READ MORE

  7. 25. Pressurised Fluid Extraction of Bioactive Species in Tree Barks : Analysis using Hyphenated Electrochemical Mass Spectrometric Detection

    Author : Michelle Co; Charlotta Turner; Per J.R Sjöberg; Kari Hartonen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pressurised fluid extraction; antioxidants; DPPH; water; ethanol; antioxidant activity; antioxidant capacity; electrochemial detection; mass spektrometry; Chemistry; Kemi; Analytical Chemistry; Analytisk kemi;

    Abstract : Analytical chemistry has developed throughout time to meet current needs. At present, the interest in biorefinery is growing, due to environmental awareness and the depletion of fossil resources. Biomass from agricultural and forestry industries has proven to be excellent raw material for different processes. READ MORE