Search for dissertations about: "tangle"

Showing result 1 - 5 of 12 swedish dissertations containing the word tangle.

  2. 1. Protein phosphatases and kinases implicated in Alzheimer's disease abnormal tau phosporylation

    Author : Jin-jing Pei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis describes the distribution, levels and activities of a number of protein kinases and protein phosphatases (PPs) implicated in the abnormal phosphorylation of the tau protein that forms the paired helical filaments (PHFs) of Alzheimer's disease (AD) neurofibrillary tangles (NFTs). Paper I describes the immunocytochemical localization of PP-1, PP-2A, PP-2B and PTP-1B, as well as the protein kinase MAP kinase and p34cdc2 in the hippocampal formation of AD and control brains. READ MORE

  4. 2. Searing apparent surfaces : infernal females in four early works of William Blake

    Author : Dee Drake; Alicia Ostriker; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; English language; Engelska språket; English; engelska;

    Abstract : This study explores the quality of the infernal as a specifically female expression of desire in William Blake's work. The contention is that the infernal constitutes an essential female element of the divine in Blake's early work but is demonized in the late work as an attribute of the Female Will. READ MORE

  5. 3. CSF biomarkers reflecting beta-amyloid and axonal pathology in Alzheimer's disease and related conditions

    Author : Niklas Mattsson; Göteborgs universitet; []
    Keywords : Alzheimer s disease; biomarker; cerebrospinal fluid; beta-amyloid; axonal; Niemann-Pick type C; neuroborreliosis;

    Abstract : Cerebrospinal fluid (CSF) biomarkers may be used to identify and monitor pathological processes in the central nervous system. CSF biomarkers in Alzheimer’s disease (AD) include β-amyloid 42 (Aβ42), total-tau (T-tau) and phosphorylated-tau (P-tau), reflecting brain amyloid, axonal and tangle pathology, respectively. READ MORE

  6. 4. Biomarkers for Alzheimer's disease and the APOE polymorphism

    Author : Ronald Lautner; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; Biomarkers; APOE; Cerebrospinal fluid; β-amyloid;

    Abstract : Alzheimer’s disease (AD) is the most common form of dementia and cerebrospinal fluid (CSF) biomarkers reflecting the core pathology of AD are now widely used for diagnosis making, in particular β-amyloid[1-42] (Aβ42) reflecting amyloid plaque pathology, phosphorylated tau (P-tau) reflecting neurofibrillary tangle pathology and total tau (T-tau) reflecting general neurodegeneration. In addition, blood-based biomarkers for AD are in the pipeline with recent studies showing promising diagnostic potential. READ MORE

  7. 5. Governing Ecologies : Species Protection in Overlapping and Contiguous Legal Regimes

    Author : Yaffa Epstein; Jan Darpö; Christina Allard; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Abstract : The Directive on the conservation of natural habitats and of wild fauna and flora (Habitats Directive) aims to protect biodiversity in the European Union. It does so within a complex ecology of legal regimes for environmental protection at the international, EU, national, and regional levels. READ MORE