Search for dissertations about: "telomere loss"
Showing result 1 - 5 of 17 swedish dissertations containing the words telomere loss.
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1. LIVING WITH PARASITES: AVIAN MALARIA, TELOMERE LENGTH AND LIFE HISTORY TRADE-OFFS
Abstract : Haemosporidia is a well-studied group of parasites, which infect mammals, reptiles and birds and use blood sucking vectors for their transmission. By conducting natural population studies and experimental infections, We have been able to detect and quantify Haemosporidia from avian blood to investigate how these pathogens affect their avian hosts. READ MORE
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2. Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii
Abstract : Telomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins. READ MORE
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3. Mediator and its role in non-coding RNA and chromatin regualtion
Abstract : Mediator is a multiprotein complex required for the regulation of RNA Polymerase II (Pol II) transcription. Mediator transmits regulatory signals from activators and repressors to the Pol II machinery at the promoter, but the complex has also many other functions related to control of gene transcription. READ MORE
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4. PARN - A Tale of A de-Tailor : Functional importance of poly(A) degradation in developmental and telomere biology disorders
Abstract : Poly(A)-specific ribonuclease (PARN) is a eukaryotic 3’-5’exoribonuclease that removes poly(A) tails of many coding and non-coding RNAs. In this thesis, we have studied the physiological role of PARN. READ MORE
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5. Towards ribozyme-mediated gene therapy of HIV-1 infections
Abstract : HIV-1 is the causative agent in AIDS, the world's fourth most frequent cause of death. HIV is a retrovirus that primarily infects macrophages and T helper cells - required for a proper immune response. READ MORE