Search for dissertations about: "the thesis of liver cancer"

Showing result 1 - 5 of 288 swedish dissertations containing the words the thesis of liver cancer.

  2. 1. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease

    Author : Moa Lindgren; Hanna Nyström; Ingrid Ljuslinder; Malin Sund; Kristian Pietras; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; breast cancer; breast cancer metastases; tumor marker; biomarker; stroma; type IV collagen;

    Abstract : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. READ MORE

  4. 2. Colorectal Liver Metastases : Onco-surgical Strategies & Prognostic Factors

    Author : Petter Frühling; Bengt Isaksson; Ville Sallinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; liver metastases; chemotherapy; oncological treatment; prognostic factors; predictive model; simultaneous resection; liver-first; colorectal-first;

    Abstract : The management of patients with colorectal cancer with liver metastases has improved over the past decades. There have been significant developments in terms of surgery, local therapies, anesthesia and oncological treatment. Nevertheless, there is no consensus on what constitutes optimal treatment strategy. READ MORE

  5. 3. Ultrasound based shear wave elastography of the liver : a non-invasive method for evaluation of liver disease

    Author : Marie Byenfeldt; Anders Elvin; Per Fransson; Odd Helge Gilja; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometric measurement; diagnostic imaging; elasticity imaging technique; blood supply; BMI; body position; fatty liver; liver disease; hepatic steatosis; liver fibrosis; liver stiffness; obesity; postural change; pressure; probe; sex characteristic; shear wave elastography; skin-to-liver capsule distance; transducer and ultrasonography; Radiography; radiografi;

    Abstract : Background: Detecting liver disease at an early stage is important, given that early intervention decreases the risk of developing cirrhosis and subsequently hepatocellular cancer (HCC). The non-invasive ultrasound-based shear wave elastography (SWE) has been used clinically for a decade to assess liver stiffness. READ MORE

  6. 4. Wnt-5a signaling in breast cancer metastasis

    Author : Annette Säfholm; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; patologisk anatomi; General pathology; cancer; onkologi; Cytologi; breast cancer; Wnt-5a; migration; pathological anatomy; metastasis; signal transduction; peptides; Cytology; cancerology; oncology;

    Abstract : Breast cancer is the most common form of malignancy affecting women in the Western world. Today, anticancer treatment can control primary breast tumors, but treatment and prevention of metastatic disease still represents a major challenge in the management of breast cancer patients. READ MORE

  7. 5. Affibody-Based Molecular Imaging and Targeted Therapy of HER3-Expressing Cancer

    Author : Sara Sophie Rinne; Anna Orlova; Vladimir Tolmachev; Mohamed Altai; Anzhelika Vorobyeva; Melpomeni Fani; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular Imaging; PET; SPECT; Cancer; Affibody; HER3; Targeted Therapy;

    Abstract : The human epidermal growth factor receptor type 3 (HER3) is overexpressed in different types of cancer and is a known contributor to disease progression and resistance to cancer therapy. This thesis is based on five original articles, which aimed to improve the diagnostic and therapeutic potential of affibody-based agents for management of HER3-expressing cancers. READ MORE