Search for dissertations about: "thesis in antibiotic resistance of pathogens"

Showing result 1 - 5 of 91 swedish dissertations containing the words thesis in antibiotic resistance of pathogens.

  2. 1. Development and Stability of Antibiotic Resistance

    Author : Maria Sjölund; Lars Engstrand; Dan Andersson; Pentti Huovinen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; antibiotic resistance; selection; mutation frequency; biological cost of resistance; compensatory evolution; Helicobacter pylori; normal microbiota; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : Antibiotic resistance is of current concern. Bacteria have become increasingly resistant to commonly used antibiotics and we are facing a growing resistance problem. The present thesis was aimed at studying the impact of antibiotic treatment on pathogenic bacteria as well as on the normal human microbiota, with focus on resistance development. READ MORE

  4. 2. Antibiotic susceptibility and resistance in Neisseria meningitidis : phenotypic and genotypic characteristics

    Author : Sara Thulin Hedberg; Magnus Unemo; Per Olcén; Hans Fredlund; Ian Feavers; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neisseria meningitidis; meningococcal disease; antibiotic resistance; antibiotic susceptbility; biological cost; PCR; sequencing; Molecular biology; Molekylärbiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; Medical microbiology; Medicinsk mikrobiologi; Bacteriology; Bakteriologi; Biomedicin; Biomedicine; Medicin; Medicine;

    Abstract : Neisseria meningitidis, also known as the meningococcus, is a globally spread obligate human bacterium causing meningitis and/or septicaemia. It is responsible for epidemics in both developed and developing countries. READ MORE

  5. 3. Selection of Resistance at very low Antibiotic Concentrations

    Author : Erik Gullberg; Dan I Andersson; Diarmaid Hughes; Linus Sandegren; Laura Piddock; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; Selection; Antibiotic resistant bacteria; Minimal inhibitory concentration; Heavy metals; Conjugative plasmid; ESBL; Mikrobiologi; Microbiology; Biology with specialization in Microbiology; Biologi med inriktning mot mikrobiologi; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Abstract : The extensive medical and agricultural use and misuse of antibiotics during the last 70 years has caused an enrichment of resistant pathogenic bacteria that now severely threatens our capacity to efficiently treat bacterial infections. While is has been known for a long time that high concentrations of antibiotics can select for resistant mutants, less is known about the lower limit at which antibiotics can be selective and enrich for resistant bacteria. READ MORE

  6. 4. Evolution of Antibiotic Resistance

    Author : Franziska Pietsch; Diarmaid Hughes; Josep Casadesús; Uppsala universitet; []
    Keywords : ciprofloxacin; rifampicin; bacterial fitness; compensation; mutation rate; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : The emergence of antimicrobial resistance is a major global threat to modern medicine. The rapid dissemination of resistant pathogens and the associated loss of efficacy of many important drugs needs to be met with the development of new antibiotics and alternative treatment options. READ MORE

  7. 5. On the Origins of mobile Antibiotic Resistance Genes : A comparative genomics approach

    Author : Stefan Ebmeyer; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotic resistance; comparative genomics; bacterial genomics; antibiotic resistance genes;

    Abstract : Mobile antibiotic resistance genes (ARGs), transferable between bacterial cells, are major contributors to the antibiotic resistance crisis we are facing today. From which organisms pathogens acquired these genes is mostly unknown, yet knowledge about their origin is needed in order to limit the emergence and spread of novel ARGs in the future. READ MORE