Search for dissertations about: "thesis in malaria immune response"
Showing result 1 - 5 of 31 swedish dissertations containing the words thesis in malaria immune response.
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1. Malaria and relapsing fever Borrelia : interactions and potential therapy
Abstract : Infectious diseases such as malaria and relapsing fever borreliosis (RF), cause severe human mortality and morbidity in developing countries. Malaria, caused by Plasmodium spp. parasites, is estimated by the World Health Organization to cause 1.5-2. READ MORE
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2. Novel immunization strategies and interethnic differences in response to malaria infection
Abstract : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. READ MORE
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3. T cell and antibody responses in Plasmodium falciparum malaria and their relation to disease susceptibility
Abstract : Malaria antigen-induced polarization of T cells into effectors Th1 and/or Th2 cells and their subsequent release of cytokines is known to affect antibody production. This thesis includes studies on early innate responses to the parasite, with a focus on γδT cells, and acquired specific responses in African sympatric ethnic tribes. READ MORE
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4. Immune Regulation During Malaria Infection
Abstract : Malaria is the largest parasitic disease in the world and is caused by the protozoon Plasmodium. The most severe form in humans is caused by Plasmodium falciparum. Immunity to malaria involves both cell-mediated and humoral responses and develops slowly over a period of ten to fifteen years, requiring repeated infections. READ MORE
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5. Vaccine development strategies applied to the Plasmodium falciparum malaria antigen 332
Abstract : Malaria is one of the major infectious diseases in the world with regard to mortality and morbidity, and the development of a vaccine against the malaria parasite Plasmodium falciparum is considered of high priority. The aim of the work presented in this thesis was to develop and characterize recombinant vaccine constructs based on the P. READ MORE