Search for dissertations about: "thesis in ovarian tumor"

Showing result 1 - 5 of 91 swedish dissertations containing the words thesis in ovarian tumor.

2. 1. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes

   Author : Alireza Labani Motlagh; Lucia Mincheva-Nilsson; Ola Winqvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

   Abstract : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. READ MORE

4. 2. Ovarian cancer : Treatment results, prognostic factors, and tumor marker surveillance

   Author : Thomas Högberg; Claes Tropé; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : The total population-based material of 426 ovarian malignancies in the Southeast Health Care Region of Sweden during 1984-1987 was surveyed. It seems that with a program of cytoreductive surgery followed by a cisplatinum chemotherapy combination in the metastasizing cases the overall survival figures have improved. READ MORE

5. 3. Mechanisms for immune escape in epithelial ovarian cancer

   Author : Pernilla Israelsson; Ulrika Ottander; Lucia Mincheva-Nilsson; Eva Lundin; Ivan Nagaev; Karin Sundfeldt; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; ovarian cancer; high-grade serous cancer; EOC; HGSC; HGSOC; tumor microenvironment; immune escape; immune suppression; cytokines; exosomes; NKG2D; MICA B; ULBP1-3; DNAM-1; surgery; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. READ MORE

6. 4. Pharmacogenetic Studies of Paclitaxel in Ovarian Cancer : focus on interindividual differences in pharmacodynamics and pharmacokinetics

   Author : Henrik Green; Curt Peterson; Peter Söderkvist; Per Rosenberg; Håkan Melhus; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacogenetics; paclitaxel; LC MS; Taxol; ovarian cancer; pharmacokinetics; CYP2C8; CYP3A4; ABCB1; äggstockscancer; paklitaxel; Clinical pharmacology; Klinisk farmakologi;

   Abstract : Ovarian cancer is one of the most common female cancer diseases in the world today and in Sweden more than 800 new cases are diagnosed every year. The standard treatment consists of chemotherapy with paclitaxel in combination with carboplatin after initial cytoreductive surgery. READ MORE

7. 5. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors

   Author : Yihong Zhu; Göteborgs universitet; []
   Keywords : junction; claudin; ovarian surface epithelium; epithelial ovarian tumor; TGF-?1;

   Abstract : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. READ MORE