Search for dissertations about: "thesis in tuberculosis PDF"

Showing result 1 - 5 of 89 swedish dissertations containing the words thesis in tuberculosis PDF.

  2. 1. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Author : Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE

  4. 2. Fighting Tuberculosis – : Structural Studies of Three Mycobacterial Proteins

    Author : Alina Castell; Torsten Unge; Manfred Weiss; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mycobacterium tuberculosis; Rv0216; Rv0130; Mycobacterium smegmatis; branched chain aminotransferase; X-ray crystallography; fatty acid metabolism; Structural biology; Strukturbiologi;

    Abstract : This thesis presents the cloning, purification, crystallization, and structural studies of two unknown proteins from Mycobacterium tuberculosis, and of an aminotransferase from Mycobacterium smegmatis. Structural knowledge of these proteins is of highest interest for structure-based drug design, which is one of the approaches that can be used in order to fight tuberculosis (TB). READ MORE

  5. 3. Tuberculosis infection in pregnant women

    Author : John Walles; Klinisk infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; Pregnancy; Latent; stillbirth; preeclampsia; QuantiFERON;

    Abstract : .... READ MORE

  6. 4. Pharmacometric models to inform dose selection and study design : Applied in hemophilia and tuberculosis

    Author : Alan Faraj; Ulrika S. H. Simonsson; Joakim Nyberg; Ron Mathot; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug development; pharmacometrics; pharmacokinetics; pharmacodynamics; non-linear mixed effect models; hemophilia; tuberculosis; dose selection; study design; pediatric extrapolation;

    Abstract : While tuberculosis is a global pandemic, hemophilia is a rare disease which many have not heard of. Due to tuberculosis mainly being a problem in developing countries and hemophilia being a rare disease, they are not as heard of as other diseases such as cancer or metabolic diseases which are on the rise in Western societies. READ MORE

  7. 5. Antimicrobial peptide therapy for tuberculosis infections

    Author : Komal Umashankar Rao; Medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculosis; antimicrobial peptides; mode of action; nanoparticles; novel therapy; membrane active peptides;

    Abstract : Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. READ MORE