Search for dissertations about: "thesis on head and neck cancer pathology"

Showing result 1 - 5 of 7 swedish dissertations containing the words thesis on head and neck cancer pathology.

  2. 1. Squamous cell carcinoma of the head and neck, focusing on Epstein-Barr-virus, programmed cell death ligand 1 and serum lipoproteins

    Author : Torben Wilms; Karin Nylander; Xiaolian Gu; Linda Boldrup; Keith Hunter; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oral tongue cancer; squamous cell carcinoma; head and neck; Epstein Barr Virus; PD-L1; lipoprotein; Oncology; onkologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi; Pathology; patologi; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; immunologi; Immunology;

    Abstract : Background: Squamous cell carcinoma of the head and neck (SCCHN)comprises a large group of tumours including the oral cavity and nasopharyngealarea, and typically affects older males in association with alcohol/tobacco usage.Within the oral cavity, the mobile tongue is the most common site for tumourdevelopment. READ MORE

  4. 2. Studies on the biological functions of interaction between components in Wnt, TGF-β and HIF pathways for cancer progression

    Author : Karthik Aripaka; Maréne Landström; Jonas von Hofsten; Carl-Henrik Heldin; Ruth Palmer; Lars-Gunnar Larsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TRAF6; HIF-1α; HIF-2α; HIF-3α; ALK5; Wnt3a; Hypoxic signalling; TGF-β; zebrafish; β-Catenin; Pathology; patologi; Oncology; onkologi;

    Abstract : Cancer is a disease that involves aggressive changes in the genome and aberrant signals between the living cells. Signalling pathways such as TGF-β (Transforming growth factor-β), Wnt, EGF (epidermal growth factor) and HIF (Hypoxia-inducible factor) evolved to regulate growth and development in mammals. READ MORE

  5. 3. p63 and epithelial homeostasis : studies of p63 under normal, hyper-proliferative and malignant conditions

    Author : Xiaolian Gu; Karin Nylander; Antonio Costanzo; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; p63; psoriasis; SCCHN; epithelium; homeostasis; Pathology; Patologi; patologi; Pathology;

    Abstract : Background: The p63 gene is a member of the p53 transcription factor family and can produce six different proteins using two promoters and differential splicing. Expression of p63 is required for proper formation of epithelial tissues. READ MORE

  6. 4. p63 – from expression to function : studies of normal oral mucosa and squamous cell carcinoma of the head and neck

    Author : Niklas Thurfjell; Karin Nylander; Phillip Coates; Göran Roos; Luisa Guerrini; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; p63; SCCHN; p53; BRCA1; Pathology; Patologi;

    Abstract : The human p63 gene discovered in 1997 encodes a series of protein isoforms that differ in their N- and/or C-terminal sequences. These isoforms have widely differing properties in promoting or repressing p53-related functions such as growth arrest and apoptosis. READ MORE

  7. 5. Diagnostic and prognostic markers in primarily non-smoking related head and neck cancer

    Author : Mark Zupancic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Head and neck cancer (HNC) includes cancers of the oral cavity, the pharynx (i.e., the nasopharynx, the oropharynx, and the hypopharynx), the larynx, the nasal cavity, the paranasal sinuses, and the salivary glands. READ MORE