Search for dissertations about: "thesis on hplc method development and validation"

Found 2 swedish dissertations containing the words thesis on hplc method development and validation.

  1. 1. Development and Validation of HPLC Methods for Analytical and Preparative Purposes

    Author : Johan Lindholm; Torgny Fornstedt; Karin Caldwell; Karl-Gustaf Wahlund; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; High performance liquid chromatography HPLC ; Analytical biotechnology; Sample preparation; Diode-array-detection DAD ; Mass spectrometry MS ; Validation; Preparative chromatography; Competitive isotherm parameters; Perturbation peak PP method; Kemi; Chemistry; Kemi;

    Abstract : This thesis concerns the development and validation of high performance liquid chromatography (HPLC) methods aimed for two industrially important areas: (i) analysis of biotechnological synthesis and (ii) determination of adsorption isotherm parameters. There is today a lack of detailed recommendations for analytical procedures in the field of biotechnological production of drugs. READ MORE

  2. 2. Adsorption Isotherm Parameter Estimation in Nonlinear Liquid Chromatography

    Author : Patrik Forssén; Bertil Gustafsson; Torgny Fornstedt; Georges Guiochon; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; High performance liquid chromatography HPLC ; Preparative chromatography; Competitive adsorption isotherm parameters; Perturbation peak PP method; Inverse method IM ; Computer simulation; Parameter estimation; Numerical method; Scientific Computing; Beräkningsvetenskap;

    Abstract : This thesis concerns the development and validation of methods for the industrially important area of adsorption isotherm parameter estimation in preparative, nonlinear high performance liquid chromatography (HPLC). Preparative chromatography is a powerful separation method to get pure compounds from more or less complex liquid mixtures, e.g. READ MORE