Search for dissertations about: "thesis on method development and validation of single drug"

Found 3 swedish dissertations containing the words thesis on method development and validation of single drug.

  2. 1. Development and Validation of Methods for Characterization of Multi-Component Systems in Preparative LC

    Author : Robert Arnell; Torgny Fornstedt; Andreas Seidel-Morgenstern; Uppsala universitet; []
    Keywords : Analytical chemistry; Liquid chromatography; Preparative LC; Chiral LC; Multi-component LC; Adsorption isotherm; Tracer-pulse method; Inverse method; Inverse method on plateaus; Peak deformations; Chiral drug-protein interactions; Analytisk kemi;

    Abstract : This thesis concerns the development and validation of methods for characterization of multi-component preparative LC systems. Measurements of competitive adsorption isotherms are performed to gain detailed information about the interactions inside the chromatography column. READ MORE

  4. 2. Proximity Extension Assay : a universal tool for proteomics in precision medicine

    Author : Phathutshedzo M. Muthelo; Ulf Landegren; Jochen Schwenk; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proximity Extension Assay; Precision medicine; Assay development; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Precision medicine aims to utilise biomarkers to ensure the right treatment is given to the right patient at the right time. In pursuit of this goal, sensitive protein detection is essential to improve opportunities for discovery, verification, validation and development of valuable protein biomarkers. READ MORE

  5. 3. Chemical proteomics for drug target deconvolution and to study biological systems

    Author : Christian M Beusch; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mass spectrometry-based proteomics has become an irreplaceable method for the unbiased and system-wide study of protein chemistry. As modern proteomics methods can not only be applied to quantify protein expression levels, but also monitor changes in post-translational modifications, subcellular localization, turnover rate, and lastly protein structures, it has become a method of choice for drug discovery and dissecting cellular processes. READ MORE