Search for dissertations about: "thesis on phage"
Showing result 1 - 5 of 132 swedish dissertations containing the words thesis on phage.
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1. Site-specific recombination of P2-like phages; possible tools for safe gene therapy : A focus on phage ΦD145
Abstract : P2-like bacteriophages integrate their genome into the E. coli host cell by a site-specific recombination event upon lysogenization. The integrative recombination occurs between a specific sequence in the phage genome, attP, and a specific sequence in the host genome, attB, generating the host-phage junctions attL and attR. READ MORE
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2. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli
Abstract : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. READ MORE
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3. Towards novel applications for biomolecular interactions at surfaces
Abstract : The focus of this thesis has been to examine two new concepts involving the interaction of biological agents with synthetic material surfaces.The feasibility of deploying phage display techniques for the screening of materials in non-biological media was examined in two studies. READ MORE
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4. The biology of filamentous phage infection - implications for display technology
Abstract : Phage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. READ MORE
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5. Molecular Recognition in Antibody Engineering. Studies on recombinant and phage displayed antibodies
Abstract : In vitro generation of antibody fragments of desired specificity and affinity plays an important role since it permits the generation of reagents which may be valuable for diagnostic and therapeutic applications. Furthermore, the kinetic parameters for an antibody-antigen interaction, rather than the affinity, has shown to correlate with biological functions like virus neutralization. READ MORE