Search for dissertations about: "transcripts"

Showing result 1 - 5 of 451 swedish dissertations containing the word transcripts.

  1. 1. Quantitative analysis of melanoma transcripts : with emphasis on methodological and biological variation

    Author : Malin Farnebäck; Håkan Hedman; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The introduction of RT-PCR made it possible to detect circulating tumor cells in melanoma patients by analysis of melanoma-associated transcripts, especially tyrosinase. Since the development of the first PCR method for tyrosinase mRNA, several studies have presented varying results. READ MORE

  2. 2. Molecular Characterization of Experimental Traumatic Brain Injury

    Author : Charlotte Israelsson; Ted Ebendal; Lars Hillered; Anders Lewén; Henrik Hagberg; Uppsala universitet; []
    Keywords : Neurosciences; traumatic brain injury; transcripts; GeneChip; chemokine; inflammation; mouse brain; neuroprotection; neuronal injury; neuroregeneration; astrocytosis; Neurovetenskap;

    Abstract : Traumatic brain injury (TBI) is the most common cause of mortality and disability in the younger (.... READ MORE

  3. 3. Analysis of human gene transcripts : Identification and characterisation based on homology and differential expression

    Author : Jacob Odeberg; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioengineering; Bioteknik;

    Abstract : .... READ MORE

  4. 4. Expression and Mutation Analyses of Candidate Cancer Genes In Situ

    Author : Sara Kiflemariam; Tobias Sjöblom; Fredrik Pontén; Mef Nilbert; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; in situ; in situ hybridization; padlock probes; mRNA; tyrosine kinases; tyrosine phosphatases; fusion transcripts;

    Abstract : Cancers display heterogeneity in genetic profiles of the individual cancer cells and in the composition of different malignant and non-malignant cell populations. Such intra-tumor heterogeneity plays a role in treatment response and the emergence of resistance to cancer therapies. READ MORE

  5. 5. On diverse biophysical aspects of genetics : from the action of regulators to the characterization of transcripts

    Author : Aymeric Fouquier D´Hérouel; Erik Aurell; Felix Ritort; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transcription regulation; regulatory motifs; binding affinity; genetic interactions; secondary structure; sequence repeats; transcript characterization; Biological physics; Biologisk fysik;

    Abstract : Genetics is among the most rewarding fields of biology for the theoretically inclined, offering both room and need for modeling approaches in the light of an abundance of experimental data of different kinds. Many aspects of the field are today understood in terms of physical and chemical models, joined by information theoretical descriptions. READ MORE