Search for dissertations about: "transfection"

Showing result 1 - 5 of 179 swedish dissertations containing the word transfection.

  2. 1. Approaches to Pharmacological Treatment and Gene Therapy of Cystic Fibrosis

    Author : Anca Dragomir; Godfried M. Roomans; Robert Dormer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; airway epithelium; colchicine; cystic fibrosis; chloride transport; genotype; heparin; phenotype; transfection; X-ray microanalysis; Anatomi; Anatomy; Anatomi;

    Abstract : Cystic fibrosis (CF) is the most common lethal genetic disease in the white population. It is due to mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), a protein that functions mainly as a cAMP-activated chloride channel. READ MORE

  4. 2. Biosynthesis, Processing, and Sorting of Human Neutrophil Granule Proteins. Focus on Cathepsin G, Proteinase 3, and Azurocidin

    Author : Daniel Garwicz; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; differentiation; bone marrow progenitor cells; preproform; mutations; Cell lines; transfection; extracellulära vätskor;

    Abstract : The neutrophil granulocyte contains a number of multifunctional proteins stored in different subsets of granules. The azurophil granules, synthesized early during differentiation, harbour leukocyte elastase, cathepsin G, proteinase 3, and azurocidin; the members of the serprocidin family. READ MORE

  5. 3. Functional Cyclic Carbonate Monomers and Polycarbonates : Synthesis and Biomaterials Applications

    Author : Jonas Mindemark; Tim Bowden; Andrew Dove; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA condensation; gene delivery; ionomers; polyplexes; self-assembly; amphiphiles; biodegradable; biological applications of polymers; transfection; cyclic carbonate monomers; polycarbonates; semicrystalline polymers; click chemistry; triazoles; cycloaddition; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

    Abstract : The present work describes a selection of strategies for the synthesis of functional aliphatic polycarbonates. Using an end-group functionalization strategy, a series of DNA-binding cationic poly(trimethylene carbonate)s was synthesized for application as vectors for non-viral gene delivery. READ MORE

  6. 4. Comparative Cell Biology in Diplomonads

    Author : Elin Einarsson; Staffan Svärd; Scott Dawson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Giardia intestinalis; Spironucleus salmonicida; intestinal parasite; hydrogenosome; encystation; gene regulation; transfection; diplomonad; antigenic variation; annexin;

    Abstract : The diplomonads are a diverse group of eukaryotic flagellates found in microaerophilic and anaerobic environments. The most studied diplomonad is the intestinal parasite Giardia intestinalis, which infects a variety of mammals and cause diarrheal disease. READ MORE

  7. 5. Hidden Diversity Revealed : Genomic, Transcriptomic and Functional Studies of Diplomonads

    Author : Jon Jerlström-Hultqvist; Staffan Svärd; Adrian Hehl; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia intestinalis; Spironucleus salmonicida; Spironucleus barkhanus; intestinal parasite; hydrogenosome; mitosome; lateral gene transfer; horizontal gene transfer; diplomonad; metamonad; sexual recombination; transfection; protein complex purification; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Abstract : The diplomonads are a diverse group of eukaryotic microbes found in oxygen limited environments such as the intestine of animals were they may cause severe disease. Among them, the prominent human parasite Giardia intestinalis non-invasively colonizes the small intestine of humans and animals where it induces the gastrointestinal disease giardiasis. READ MORE