Search for dissertations about: "translational research"
Showing result 1 - 5 of 184 swedish dissertations containing the words translational research.
-
1. Translational Research of Mendelian Disorders : Applications of Cutting-Edge Sequencing Techniques and Molecular Tools
Abstract : Up to 8% of all live-born children are affected with a congenital disorder. Some are Mendelian disorders of known etiology, but many are of undetermined genetic cause and mechanism, limiting diagnosis and treatment. READ MORE
-
2. Advanced Genomic Tools in Translational Research of Neurodevelopmental Disorders
Abstract : Neurodevelopmental disorders (NDDs) affect >4.7% of individuals world-wide. Most cases are expected to have an underlying genetic cause. However, only 36–40% of those affected get a genetic diagnosis through exome sequencing. READ MORE
-
3. Building the Bridge from Bench to Bedside: Ethical Issues in Translational Stem Cell Research
Abstract : Abstract in UndeterminedTranslational stem cell research raises many interesting ethical questions, which have, to a greater or lesser degree, been debated at an international as well as at an interdisciplinary level. Nevertheless, there is still no international consensus regarding how a number of ethical questions related to this research should be answered. READ MORE
-
4. Translational research of the quaking gene : Focusing on the conjunction between development and disease
Abstract : Quaking (QKI) is an RNA binding protein involved in the post-transcriptional regulation of gene expression. Originally identified as the cause of hypomyelination in a mouse mutant, it has since been consistently implicated in a wide range of neurological diseases. READ MORE
-
5. Multicellular Tumour Spheroids in a Translational PET Imaging Strategy
Abstract : Positron Emission Tomography (PET) has gained an important roll in clinical for diagnosis, staging and prognosis of a range of cancer types. Utilization of PET for monitoring and evaluation of cancer treatment is an attractive but almost new concept. The proper choice of PET-tracer as a biomarker for treatment follow-up is crucial. READ MORE