Search for dissertations about: "transmembrane helix"

Showing result 1 - 5 of 42 swedish dissertations containing the words transmembrane helix.

  2. 1. Transmembrane helices : tails, turns and snorkels

    Author : Magnus Monné; Donald Engelman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : The assembly and structure of membrane proteins are intimately related. Targeting and insertion of membrane proteins into the endoplasmatic reticulum (ER) membrane involve many components that facilitate the folding of the native structure. READ MORE

  4. 2. Studies on the Conformation of Transmembrane Polypeptides in Membrane Proteins

    Author : Marika Cassel; Gunnar von Heijne; Martin Spiess; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein; topology; transmembrane helix; helical hairpin; turn propensity; Biochemistry; Biokemi;

    Abstract : The major aim of the studies that this thesis is based on has been to better define the topological determinants of the formation of so-called helical hairpins during membrane protein assembly in the ER membrane.The helical hairpin is a basic folding unit in membrane proteins. READ MORE

  5. 3. Marginally hydrophobic transmembrane α-helices shaping membrane protein folding

    Author : Tuuli Minttu Virkki de Marothy; Arne Elofsson; William Dowhan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein folding; hydrophobicity; translocon; transmembrane helix; marginally hydrophobic transmembrane helices; orientational preference; positive inside rule; aquaporin 1; Biochemistry; biokemi;

    Abstract : Most membrane proteins are inserted into the membrane co-translationally utilizing the translocon, which allows a sufficiently long and hydrophobic stretch of amino acids to partition into the membrane. However, X-ray structures of membrane proteins have revealed that some transmembrane helices (TMHs) are surprisingly hydrophilic. READ MORE

  6. 4. Steady, ready, go - proteomics of etioplast inner membranes reveals a high readiness for light

    Author : Lisa A. Blomqvist; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chloroplast; etioplast; NADPH:protochlorophyllide oxidoreductase; prolamellar body; proteomics; prothylakoid; transmembrane; Triticum aestivum; wheat;

    Abstract : Light is essential for development of photosynthetically active chloroplasts. In the absence of light proplastids develop into etioplasts which are readily transformed into chloroplasts upon illuminat... READ MORE

  7. 5. Translocation of proteins into and across the bacterial and mitochondrial inner membranes

    Author : Salomé Calado Botelho; Gunnar von Heijne; Walter Neupert; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; mitochondria; Saccharomyces cerevisiae; SecYEG; TIM23; transmembrane helix; Biochemistry; biokemi;

    Abstract : Translocons are dynamic protein complexes with the ability to respond to specific signals and to transport polypeptides between two distinct environments. The Sec-type translocons are examples of such machineries that can interconvert between a pore forming conformation that translocates proteins across the membrane, and a channel-like conformation that integrates proteins into the membrane by lateral opening. READ MORE