Search for dissertations about: "transport barrier"
Showing result 1 - 5 of 213 swedish dissertations containing the words transport barrier.
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1. Collisional transport in edge transport barriers and stellarators
Abstract : Nuclear fusion has the potential to generate abundant and clean energy. In magnetic confinement fusion, the temperatures needed to achieve fusion are obtained by confining a hot plasma with magnetic fields. READ MORE
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2. Blood-Brain Barrier Transport : Investigation of Active Efflux using Positron Emission Tomography and Modelling Studies
Abstract : This thesis examines the transport of exogenous molecules across the blood-brain barrier (BBB), focusing on active efflux, using positron emission tomography (PET), computer simulation and modelling. P-glycoprotein (P-gp) inhibition was studied using [11C]verapamil and [11C]hydroxyurea was investigated as a new marker for active efflux transport. READ MORE
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3. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers
Abstract : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. READ MORE
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4. Overall Accessibility of Public Transport for Older Adults
Abstract : This thesis is based on four studies that explore accessibility for older adults during whole trips by public transport. The overall goal was to gain knowledge of the interrelationships among key variables and to develop a conceptual model of the overall accessibility of public transport. READ MORE
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5. Pharmacokinetics and Pharmacodynamics of Oxycodone and Morphine with Emphasis on Blood-Brain Barrier Transport
Abstract : The pharmacokinetics and pharmacodynamics of oxycodone and morphine was investigated and related to the transport across the blood-brain barrier (BBB) in rats. The influence of a P-glycoprotein (P-gp) inhibitor on the plasma pharmacokinetics and pharmacodynamics of oxycodone was evaluated. READ MORE