Search for dissertations about: "transverse relaxation"

Showing result 1 - 5 of 28 swedish dissertations containing the words transverse relaxation.

2. 1. Theory of water-proton spin relaxation in complex biological systems

   Author : Zhiwei Chang; Biofysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; spin relaxation theory; immobilized macromolecules; magnetic relaxation dispersion; integral longitudinal relaxation rate; stochastic Liouville equations; multi-spin systems; cross-mode relaxation; spectral density functions;

   Abstract : In complex biological systems (e.g. gels, cross-linked proteins and biological tissues), the longitudinal spin relaxation of water protons is primarily induced by exchange-mediated orientational randomization (EMOR) of intra- and intermolecular magnetic dipole-dipole couplings. READ MORE

4. 2. Pushing diffusion MRI towards new dimensions

   Author : Joao Martins; Fysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR; MRI; diffusion; relaxation; multidimensional diffusion MRI; relaxation-diffusion correlations; Laplace NMR; porous media; tissue microstructure; heterogeneity; anisotropy;

   Abstract : Diffusion-MRI techniques allow the non-invasive investigation of microstructural changes in living tissues. However, a detailed interpretation of the data is complicated by the fact that multiple microscopic environments with varying diffusion properties all contribute to the measured signal. READ MORE

5. 3. Degradation, Metabolism and Relaxation Properties of Iron Oxide Particles for Magnetic Resonance Imaging

   Author : Karen Briley Saebo; Håkan Ahlström; Atle Bjørnerud; Michael Knopp; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic Resonance Imaging; contrast agents; iron oxide particles; metabolism; relaxation mechanisms; Radiologisk forskning; Radiological research; Radiologisk forskning;

   Abstract : Whereas the effect of size and coating material on the pharmacokinetics and biodistribution of iron oxide based contrast agents are well documented, the effect of these parameters on liver metabolism has never been investigated. The primary purpose of this work was to evaluate the effect of iron oxide particle size and coating on the rate of liver clearance and particle degradation using a rat model. READ MORE

6. 4. Molecular dynamics studied by NMR relaxation experiments. Characterization of functional dynamics in the FK506 binding protein FKBP12

   Author : Ulrika Brath; Biofysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; nuclear magnetic resonance; NMR; FK506; protein dynamics; chemical exchange; spin relaxation; FKBP12; FKBP; isotope labeling;

   Abstract : The presented thesis work is concerned with the study of molecular dynamics using liquid nuclear magnetic resonance (NMR) spectroscopy. Spin relaxation dispersion experiments in the rotating frame (R1ρ) are employed to provide a detailed, atomic-resolution view of protein dynamics. READ MORE

7. 5. Proton Relaxation Properties of a Particulate Iron Oxide MR Contrast Agent in Different Tissue Systems : Implications for Imaging

   Author : Atle Bjørnerud; Graham A. Wright; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Iron oxide nanoparticles; USPIO; NC100150 Injection; water exchange limited relaxation; MR perfusion imaging.; Onkologi; Oncology; Onkologi; radiologi; Radiology;

   Abstract : Knowledge of the relationship between in vivo contrast agent concentration and magnetic resonance (MR) signal response is an important requirement in contrast enhanced MR imaging in general and in MR based perfusion imaging in particular. This relationship is a complex function of the properties of the contrast agent as well as the structure of the target tissue. READ MORE