Search for dissertations about: "trisaccharide"

Showing result 1 - 5 of 28 swedish dissertations containing the word trisaccharide.

  2. 1. NMR studies of Carbohydrate Structure and Dynamics in Solution

    Author : Torgny Rundlöf; Thomas Peters; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Abstract : Methods for studies of the structures of carbohydrates in solution and their dynamics are presented. Approaches employing nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), force-field computer simulations and chemical methods are described. READ MORE

  4. 2. Development of strategies for construction of thioglycoside building blocks corresponding to repeating triads of Cryptococcus neoformans GXM capsular polysaccharide

    Author : Lina Rydner; Stefan Oscarson; Olof Ramström; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Crytococcus neoformans; Capsular polysaccharide; Thioglycosides; Convergent synthesis; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis focuses on the development of methods for synthesis of thioglycoside building blocks corresponding to the repeating units of the capsular polysaccharide (CPS) of Cryptococcus neoformans, an opportunistic fungal pathogen. The building blocks are suitable for construction of large synthetic oligosaccharides related to the native CPS-structures which are to be used in biological studies in order to identify protective epitopes with the aim to develop a glycoconjugate vaccine against C. READ MORE

  5. 3. Structural and Conformational Studies of Oligo- and Polysaccharides

    Author : Mona Zaccheus; Göran Widmalm; Christina De Castro; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; structural analysis; conformational analysis; carbohydrates; polysaccharides; organisk kemi; Organic Chemistry;

    Abstract : The focus of this thesis is to examine the structural properties of polysaccharides produced by bacteria, as well as the dynamic and conformational behavior of a synthetically derived oligosaccharide.The primary structures of the O-polysaccharide repeating units of four different Escherichia coli (E. READ MORE

  6. 4. Syntheses of naturally occurring fatty acid esters of sucrose and heptose-containing oligosaccharides found in the Salmonella Ra core

    Author : Helena Ritzén; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Nine sucrose esters, acylated in the glucopyranosyl moiety, have been synthesized from the same precursor, 3-0-allyl-3',4',6'-tri-0-benzyl-4,6-0- (4-metoxybenzylidene)sucrose. The sucrose esters synthesized include the major compounds found in tobacco and potato plants, i. e. READ MORE

  7. 5. Decoding Heparan Sulfate

    Author : Johan Kreuger; John T. Gallager; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Heparan sulfate; fibroblast growth factor; receptor; endostatin; angiogenesis; interaction; sequence; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Heparan sulfate (HS) is a polysaccharide of glycosaminoglycan type composed of alternating hexuronic acid [either glucuronic acid (GlcA) or iduronic acid (IdoA)] and glucosamine (GlcN) units that can be sulfated in various positions. HS binds to a large number of proteins and these interactions promote many biological processes, including cell adhesion and growth factor signaling. READ MORE