Search for dissertations about: "trisomy"

Showing result 1 - 5 of 25 swedish dissertations containing the word trisomy.

  2. 1. Trisomies in Hematologic Malignancies

    Author : Kajsa Paulsson; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; Klinisk genetik; cytogenetik; Genetik; cytogenetics; Genetics; leukemia; chromosome aberration; trisomy;

    Abstract : Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.. READ MORE

  4. 2. Cytogenetic studies of normal kidney tissue and renal cell carcinoma

    Author : Peter Elfving; Malmö (Abrahamsson) Urologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; Klinisk genetik; Clinical genetics; nonneoplastic kidney tissue; renal cell carcinoma; trisomy 7; Cytogenetics; FISH; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. READ MORE

  5. 3. Characterization of somatic mutations in nonneoplastic cells

    Author : Karin Broberg; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; osteoarthritis; nonneoplastic; HMGIC; trisomy 7; FISH; Molecular genetics; cytogenetics; Klinisk genetik;

    Abstract : Acquired genetic alterations, of which many are visible on the chromosome level, are believed to be necessary for tumorigenesis, and most tumors display characteristic patterns of recurrent structural and numerical aberrations. However, two of the most frequently occurring chromosome mutations in malignant and benign solid tumors, i.e. READ MORE

  6. 4. Cytogenetic studies of primary and metastatic breast cancer

    Author : Adewale Adeyinka; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; histokemi; cytokemi; Histologi; tissue culture; cytochemistry; histochemistry; Histology; metastases; prognosis; male breast cancer; breast cancer; trisomy 12; Cytogenetics; chromosomes; vävnadskultur; Clinical genetics; Klinisk genetik;

    Abstract : A series of primary and metastatic breast carcinomas obtained from female and male patients were cytogenetically analysed. Trisomy 12 was identified as a recurrent and sometimes early event in breast carcinogenesis. READ MORE

  7. 5. Surgical treatment of atrioventricular septal defect

    Author : Jens Johansson Ramgren; Thoraxkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrioventricular septal defect; Surgery; Echocardiography; trisomy 21; Survival; Reoperation;

    Abstract : .... READ MORE