Search for dissertations about: "tryptase"

Showing result 1 - 5 of 30 swedish dissertations containing the word tryptase.

  2. 1. The Impact of Tryptase and Epigenetic Mechanisms on Mast Cells

    Author : Sultan Alanazi; Gunnar Pejler; Constantin Urban; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mast cells; mastocytosis; tryptase; histone; DNA; methylation; neutrophil extracellular traps; Immunologi; Immunology;

    Abstract : Mast cells have a large influence on multiple immune-mediated responses, including allergic conditions, and they have been implicated in various diseases such as arthritis and cancer. Mastocytosis is characterized by abnormal mast cell proliferation induced by mutations in KIT, the stem cell factor (SCF) receptor. READ MORE

  4. 2. Mast Cell-Mediated Orchestration of Airway Epithelial Responses in Chronic Respiratory Diseases

    Author : Frida Berlin; Respiratorisk cellbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Tryptase; Chymase; Bronchial epithelium; Respiratory diseases;

    Abstract : Chronic respiratory diseases, such as asthma, are an increasing health issue worldwide and cause about 3.9 million deaths annually. Despite this, little is know about the molecular mechanisms underpinning disease pathogenesis. READ MORE

  5. 3. The middle ear : The inflammatory response in children with otitis media with effusion and the impact of atopy : clinical and histochemical studies

    Author : David S. Hurst; Uppsala universitet; []
    Keywords : Medical sciences; Allergy; atopy; eosinophil cationic protein; IL-5; tryptase; otitis media with effusion; in vitro testing; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Otitis media with effusion (OME) is the major form of chronic relapsing inflammatory disease of the middle ear, constitutes the most common diagnosis for children under 15 years old and is the major cause of auditory dysfunction in pre-school children. OME is a disease more commonly found in allergic children. READ MORE

  6. 4. Cutting Edge – Cleavage Specificity and Biochemical Characterization of Mast Cell Serine Proteases

    Author : Ulrika Karlson; Lars Hellman; Urban Gullberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; mast cell; serine protease; tryptase; chymase; substrate specificity; phage display; Biologi; Biology; Biologi; Molecular Immunology; molekylär immunologi;

    Abstract : It is well established that mast cells (MC) are key players in airway pathologies such as allergic asthma, but they are also known to contribute to host defense and tissue remodeling. MC serine proteases are the major protein components of mast cell granules and accordingly, are most likely involved in many aspects of MC function. READ MORE

  7. 5. Mast cells and its crosstalk with mesenchymal cells in chronic lung diseases

    Author : Mariam Bagher; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; Fibroblasts; IPF; COPD; Extracellular matrix; Remodelling; Inflammation; Tryptase; Chymase; Protease-activated receptor 2; Migration;

    Abstract : .... READ MORE