Search for dissertations about: "tumor necrosis factor inhibition"
Showing result 1 - 5 of 32 swedish dissertations containing the words tumor necrosis factor inhibition.
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1. Aspects on inflammation and cardiovascular comorbidity in rheumatoid arthritis
Abstract : There is an increased risk for cardiovascular (CV) comorbidity among patients with rheumatoid arthritis (RA), with premature atherosclerosis, and a higher incidence of CV events, compared with the general population. Disease related factors add to the CV risk, and interact with the traditional CV risk factors. READ MORE
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2. Oxygen delivery and mitochondrial dysfunction as assessed by microdialysis during interventions in experimental sepsis
Abstract : Early administration of broad-spectrum antibiotics is the first goal in sepsis treatment. Besides from bacteriostatic/bactericidal effects, some antibiotics may also modify the host´s response to infection. The novel antibiotic tigecycline may exert such properties; however, this property has not been evaluated in large-animal trials. READ MORE
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3. Proteasome inhibition in the regulation of natural killer cell function and multiple myeloma cell apoptosis
Abstract : Multiple myeloma (MM) is a hematologic malignancy mostly occurring in the elderly and characterized by an expansion of monoclonal plasma cells in the bone marrow and increased monoclonal immunoglobulin in plasma. The outcome of this disease has been greatly improved due to introduction of new drugs. READ MORE
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4. Effects of lipid oxidation on transcriptional regulation and cell death
Abstract : Elevated levels of low density lipoprotein (LDL) in plasma are associated with an increased risk for atherosclerosis. Excessive accumulation of lipoproteins and lipids in the vascular wall is thought to lead to the development of advanced atherosclerotic lesions prone to rupture. READ MORE
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5. Modulation of the inflammatory response in experimental bacterial meningitis
Abstract : In bacterial meningitis, tissue damage in the central nervous system (CNS) is inflicted by the host's inflammatory response to invading pathogens, rather than by the bacteria itself. Adjuvant treatment with anti-inflammatory drugs in experimental bacterial meningitis has demonstrated beneficial effects on CNS pathology. READ MORE