Search for dissertations about: "tyrosine kinase"

Showing result 16 - 20 of 389 swedish dissertations containing the words tyrosine kinase.

  2. 16. Protein Tyrosine Phosphatases as Regulators of Receptor Ryrosine Kinases

    Author : Camilla Persson; Arne Östman; Niels Peter Moller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; protein tyrosine phosphatase; tyrosine kinase; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Tyrosine phosphorylation is a crucial mechanism in cellular signaling and regulates proliferation, differentiation, migration and adhesion. The phosphorylation reaction is reversible and is governed by two families of enzymes: protein tyrosine kinases and protein tyrosine phosphatases (PTPs). READ MORE

  4. 17. The Soluble Form of the Axl Receptor Tyrosine Kinase

    Author : Carl Ekman; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The present investigation focus on the receptor Axl, which is a member of the receptor tyrosine kinase family. Axl is activated by the ligand Gas6 inducing cell growth and proliferation, but also regulate inflammation and vascular homeostasis. READ MORE

  5. 18. Mechanistic Implications and Characterization of Anaplastic Lymphoma Kinase (ALK) mutations in Neuroblastoma

    Author : Damini Chand; Bengt Hallberg; Christer Larsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; ALK; crizotinib; receptor tyrosine kinase; molekylärbiologi; Molecular Biology;

    Abstract : Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that was first reported as a fusion partner of nucleophosmin in Anaplastic large cell lymphoma in 1994. ALK is involved in myriad of cancers including neuroblastoma which is the most common extracranial solid tumor affecting young children. READ MORE

  6. 19. The receptor tyrosine kinase Met and the protein tyrosine phosphatase PTPN2 in breast cancer

    Author : Cynthia Veenstra; Olle Stål; Gizeh Perez-Tenorio; Pietras Kristian; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Breast cancer is the most common form of cancer in women worldwide and the second leading cause of cancer death. It is a heterogeneous disease and is subdivided into different subtypes, all with different treatment responses and survival outcomes. READ MORE

  7. 20. FLT3 and KIT in acute myeloid leukemia. Translational studies on oncogenic signaling from receptor tyrosine kinases. : Translational studies on oncogenic signaling from receptor tyrosine kinases

    Author : OSCAR LINDBLAD; Avdelningen för translationell cancerforskning; []
    Keywords : Acute myeloid leukemia; FLT3-ITD; KIT; tyrosine kinase receptors;

    Abstract : .... READ MORE