Search for dissertations about: "vascular dysfunction"
Showing result 1 - 5 of 186 swedish dissertations containing the words vascular dysfunction.
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1. Vascular Dysfunction in Stroke and CADASIL
Abstract : Cerebrovascular disease (CVD) is strongly linked to hypertension and generally occurs later in life than coronary artery disease (CAD). Three quarters of the patients with symptomatic CVD are above 65 years of age. The risk factors are the same for CVD and CAD, but the relative importance of the vascular risk factors differs greatly. READ MORE
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2. Biomarkers of vascular function and structure in young healthy adults
Abstract : Atherosclerosis is a disease affecting the blood vessels in the body. Its pathophysiologic mechanisms involve infiltration of the vessel walls by fatty matter and immune cells. This process is slow, starting in childhood but typically not manifesting as symptomatic disease until late adulthood (after 60 years of age). READ MORE
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3. Vascular Effects of P2 Receptors. Changes in Congestive Heart Failure
Abstract : Extracellular nucleotides induce dilatation and constriction of blood vessels by activation of P2 receptors. In this thesis the vasomotor effects of P2 receptor activation were studied in the rat mesenteric artery, and their changes in congestive heart failure (CHF) were evaluated using in vitro pharmacology, electrophysiology and competitive RT-PCR. READ MORE
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4. Integration of signalling in smooth muscle caveolae
Abstract : Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis examine the role of caveolae in smooth muscle function. READ MORE
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5. Hemodynamic Effects of Lung Function Optimization in Experimental Acute Respiratory Distress Syndrome
Abstract : Acute Respiratory Distress Syndrome (ARDS) is a severe pulmonary inflammation affecting thousands of patients every year in Sweden and has a mortality of 30-50%. Mechanical ventilation (MV) is usually necessary, but could per se augment the inflammation and contribute to mortality. READ MORE