Search for dissertations about: "vascularization"
Showing result 1 - 5 of 60 swedish dissertations containing the word vascularization.
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1. Mechanisms of Tissue Vascularization
Abstract : Tissue neovascularization in postnatal life occurs during post-traumatic tissue healing, neoplastic growth and in the endometrium during the reproductive cycle of females. Although embryonic angiogenesis has been intensively studied, far less is known about tissue revascularization and vessel remodeling in adults due to methodological difficulties. READ MORE
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2. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans
Abstract : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. READ MORE
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3. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis
Abstract : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. READ MORE
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4. Neuropilin-1 regulation of tumor vascularization and growth
Abstract : Angiogenesis, the formation of new blood vessels from existing ones, is dysregulated during tumor progression as a result of chronic hypoxia and inflammation. Such alterations lead to a lack of vessel hierarchy, and the formation of poorly perfused, leaky and blunt-ended vessels, contributing to disease progression. READ MORE
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5. Hypoxia-Inducible Factors in Tumor Cell Differentiation and Tumor Vascularization
Abstract : Mammalian cells, including tumor cells, adapt to hypoxia via stabilization of two transcription factors - Hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha. Among other consequences, hypoxia is a main driving force behind angiogenesis. READ MORE