Search for dissertations about: "vibrio cholerae thesis"

Showing result 1 - 5 of 21 swedish dissertations containing the words vibrio cholerae thesis.

  1. 1. Modulators of Vibrio cholerae predator interaction and virulence

    University dissertation from Umeå : Umeå University

    Author : Barbro Lindmark; Umeå universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; Caenorhabditis elegans; PrtV; outer membrane vesicles; non-O1 non-O139; serum resistance; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics Molecular biology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Vibrio cholerae, the causal agent of cholera typically encodes two critical virulence factors: cholera toxin (CT), which is primarily responsible for the diarrhoeal purge, and toxin-co-regulated pilus (TCP), an essential colonisation factor. Nontoxigenic strains expressing TCP can efficiently acquire the CT gene through lysogenic conversion with CTXΦ, a filamentous phage that encodes CT and uses TCP as a receptor. READ MORE

  2. 2. Regulatory roles of sRNAs in pathogenesis of Vibrio cholerae

    University dissertation from Umeå : Umeå University

    Author : Dharmesh Sabharwal; Umeå universitet.; Umeå universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; sRNA; Biofilm; OmpT; RbmC; Vrp; VafA; mikrobiologi; Microbiology;

    Abstract : The Gram-negative pathogen Vibrio cholerae uses variety of regulatory molecules to modulate expression of virulence factors. One important regulatory element of microorganisms is small non-coding RNAs (sRNAs), which control various cell functions such as expression of cell membrane proteins, mRNA decay and riboswitches. READ MORE

  3. 3. Characterization and persistence of potential human pathogenic vibrios in aquatic environments

    University dissertation from Kristianstad : Kristianstad University

    Author : Betty Collin; Högskolan Kristianstad.; Göteborgs universitet.; University of Gothenburg.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; Vibrio parahaemolyticus; Mozambique; Sweden; molluscs; occurrence; persistence; sediment; TCBS; PCR; PhP; antibiotic resistance; microbiology; Vibrio spp.; Mytilus edulis;

    Abstract : Vibrio spp., natural inhabitants of aquatic environments, are one of the most common causes of bacterial gastroenteritis in the world, being spread to humans via the ingestion of seafood, contaminated drinking water or exposure to seawater. The majority of Vibrio spp. are avirulent, but certain strains may sporadically be human pathogenic. READ MORE

  4. 4. Structural and functional studies of the secreted metalloprotease PrtV from Vibrio cholerae

    University dissertation from Umeå : Umeå universitet

    Author : Aaron Edwin; Umeå universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cholera; Vibrio cholerae; virulence factors; PrtV; X-ray crystallography; NMR;

    Abstract : Cholera, an acute diarrheal diseases caused by the intestinal infection of the pathogenic bacterium Vibrio cholerae, continues to be a global killer in the world today. PrtV, a secreted zinc metalloprotease, is a potent cytotoxic virulence factor of V. cholerae. READ MORE

  5. 5. Development of novel vaccine strains of Vibrio cholerae and studies on the role of serotype in epidemic spread of cholera

    University dissertation from Umeå : Umeå universitet

    Author : Stefan Karlsson; Göteborgs universitet.; University of Gothenburg.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera; Vibrio cholerae; Serotype; Ogawa; Inaba; Hikojima; Vaccine; Immunogenicity; serotype switching; wbeT;

    Abstract : Cholera, caused by bacterium Vibrio cholerae O1, is a severe diarrheal disease with an estimated 3-5 million cases and more than 140 000 deaths every year particularly affecting children under 5 years of age. It can be found all over the world and often causes cholera in places where access to clean water or proper sanitary facilities are limited or compromised. READ MORE