Search for dissertations about: "viral hepatitis"

Showing result 21 - 25 of 90 swedish dissertations containing the words viral hepatitis.

  2. 21. Hepatitis B virus RNA in serum and liver tissue - quantification using digital PCR

    Author : Kasthuri Prakash; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; NTCP; HBV DNA; HBV RNA; subviral particles; integrations; droplet digital PCR;

    Abstract : Hepatitis B virus (HBV) infection is a global health issue that is responsible for approximately 900,000 deaths each year, by inducing liver cirrhosis and hepatocellular carcinoma (HCC). A few markers are used to classify HBV infection and monitor treatment efficacy, including HBV DNA, surface antigen (HBsAg) and e antigen (HBeAg) in serum as well as HBV DNA and RNA in liver tissue. READ MORE

  4. 22. Innate immunity in the immunopathogenesis of chronic viral infection

    Author : David Malone; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Natural killer (NK) cells have a key role in control and clearance of viral infections. To carry out this function NK cells are capable of recognising infected cells and responding with induction of apoptosis in these cells, and production of pro-inflammatory cytokines. READ MORE

  5. 23. HIV-1/HCV co-infection : immunity and viral dynamics

    Author : Karolin Falconer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) are the agents behind two viral epidemics causing huge morbidity and mortality worldwide. HCV infection is a leading cause of end-stage liver disease. READ MORE

  6. 24. Molecular characterization of the hepatitis C virus core protein

    Author : Priya Devi; Anders Bergqvist; Björn Olsen; Tanel Punga; Gerald McInerney; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; HCV; core protein; SHP-1; CpG methylation; bisulfite sequencing; NGS; PBMC; Ca2 NFAT; strand-specific RT qPCR; Klinisk virologi; Clinical Virology; Infektionssjukdomar; Infectious Diseases; Mikrobiologi; Microbiology; Medical Virology; Medicinsk virologi;

    Abstract : Hepatitis C virus (HCV) is an RNA virus that causes chronic infection, which can lead to hepatocellular carcinomas in humans. Besides liver diseases, the chronic HCV infection causes a broad spectrum of extrahepatic complications such as lymphoproliferative, metabolic and autoimmune disorders. READ MORE

  7. 25. Hepatitis C virus infection : molecular analysis of transmission and immunity

    Author : Tobias Allander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hepatitis C virus; Nosocomial transmission; Hemodialysis; Leukemia Envelope glycoprotein gp70; Hypervariable region 1; Antibodies; Phage display; Combinatorial antibody libraries; Neutralization.;

    Abstract : Hepatitis C virus (HCV) is an important cause for chronic liver disease worldwide. Infection by HCV may resolve spontaneously, but in the majority of cases a chronic infection is established, that may result in liver cirrhosis and hepatocellular cancer. READ MORE