Search for dissertations about: "wegener’s granulomatosis"

Showing result 1 - 5 of 11 swedish dissertations containing the words wegener’s granulomatosis.

2. 1. T lymphocytes in Wegener’s granulomatosis

   Author : Ricardo Antonio Giscombe Stephen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Wegener s granulomatosis; T lymphocytes; TCR; T cell expansions; HLA-DRB1*0401; CTLA-4; IL-10;

   Abstract : Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects small and medium size blood vessels. The respiratory tract and lungs are usually compromised with necrotizing granulomatous formations. The aetiology is unknown and untreated the prognosis of generalised WG is very poor. READ MORE

4. 2. Mechanisms of endothelial cell dysfunction in Wegener's granulomatosis

   Author : Carolina Holmén; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Wegener´s granulomatosis; vasculitis; anti-endothelial cell antibody; circulating endothelial cell; vascular adhesion protein 1; MHC class-I related chain A;

   Abstract : Vasculitides are a heterogeneous group of disorders that share a common feature of blood vessel inflammation. A major cell type of the blood vessel affected is the endothelial cell (EC). READ MORE

5. 3. Studies on the Epidemiology and Outcome of Primary Systemic Vasculitis

   Author : Aladdin Mohammad; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polyarteritis nodosa; survival; microscopic polyangiitis; arteritis; vasculitis damage index; Vasculitis; ANCA; Wegener s granulomatosis; Churg-Strauss syndrome;

   Abstract : Primary Systemic Vasculitides [PSV: Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS) and polyarteritis nodosa (PAN)] are rare systemic diseases of unknown etiology; if untreated, they are associated with high morbidity and mortality rates. Changes in the classification and diagnostic improvements during the last decades have increased reported prevalence and incidence rates of PSV. READ MORE

6. 4. Proteinase 3 and Neutrophil Apoptosis in ANCA-Associated Systemic Vasculitis

   Author : Mohamed AbdGawad; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener’s granulomatosis; anti-neutrophil cytoplasmic antibody ANCA . Proteinase 3 PR3 ; myeloperoxidase MPO . Flowcytometry FACS . Vasculitis.; microscopic polyangitis;

   Abstract : ANCA-Associated Systemic Vasculitis (AASV) is characterized by leukocytoclasis- dying neutrophils surrounding small blood vessels. Previous studies have shown increased plasma PR3 and increased proportion of neutrophils expressing plasma membrane-associated PR3 (mPR3+). READ MORE

7. 5. Diagnostic and prognostic aspects of anti-neutrophil cytoplasmic antibodies in systemic vasculitis

   Author : Daina Selga; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; epitope; Wegener s granulomatosis; microscopic polyangiitis; polyarteritis nodosa; capture ELISA; Immunology; anti-neutrophil cytoplasmic antibody; proteinase 3; vasculitis; nephrology; Urologi; nefrologi; Urology;

   Abstract : Primary systemic vasculitis is associated with a high mortality if left untreated and it is essential to make the diagnosis before permanent organ damage has occurred. In this thesis the diagnostic and prognostic significance of anti-neutrophil cytoplasmic antibodies (ANCA) in systemic vasculitis is investigated. READ MORE