Search for dissertations about: "weight drop injury"

Showing result 1 - 5 of 8 swedish dissertations containing the words weight drop injury.

2. 1. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

   Author : Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

   Abstract : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. READ MORE

4. 2. Mechanisms of traumatic brain injury in the rat : Morphological consequences and neurotrophic responses

   Author : Anders Lewén; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cortical contusion injury; TBI; neurons; axons; dendrites; APP; MAP2; BMPR-II; ActR-I; trkB; c-fos; BDNF; PACAP; TUNEL; TGFs; serine threonine; bone morphogenetic protein; neuropeptides; reactive oxygen species; ROS; apoptosis; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

   Abstract : Traumatic brain injury is a major cause of death and disability in the Western world. especially in young people. Understanding the pathophysiology of traumatic brain injury is the basis for further development of better therapeutic strategies for such patients. READ MORE

5. 3. Genetics in experimental traumatic brain injury

   Author : Faiez Al Nimer; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Traumatic brain injury (TBI) is the leading cause of death and disability in the young population in the industrialized world. It comprises a heterogeneous group of brain pathologies where head trauma initiates a series of complex molecular pathways, which, together with the initial injury, account for the final outcome. READ MORE

6. 4. Genomic clues to secondary injury mechanisms in brain trauma

   Author : Christina von Gertten; Karolinska Institutet; Karolinska Institutet; []
   Keywords : traumatic brain injury; cerebral cortical contusion; weight-drop model; depolarisation; gene expression; nestin; MMP-9; TIMP-1; osteopontin; CD44; hippocalcin; NMDA receptor; microarray; rat;

   Abstract : Traumatic brain injury (TBI) is a heterogenous disease that can lead to persistent disability or death. The immediate mechanical disruption of brain tissue is followed by a phase of secondary brain injury. During this phase TBI challenges clinical interventions due to its complexity. READ MORE

7. 5. Cell therapy for spinal cord injury, studies of motor and sensory systems

   Author : Christoph Hofstetter; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Nervous system; spinal cord injury; pseudorabies virus; axonal tracing; functional MRI; stereology; Rho-kinases; transplantation; stem cells; neurogenin2; allodynia;

   Abstract : Spinal cord injury represents a significant medical concern, affecting thousands of individuals each year. The majority of victims are young males harmed by traffic accidents, violence, and falls. Severe spinal cord injury interupts nerve fiber pathways connecting the brain and the rest of the body. READ MORE