Search for dissertations about: "$1000 genome"

Showing result 1 - 5 of 22 swedish dissertations containing the words $1000 genome.

  2. 1. Genomic Imprinting in Development and Evolution

    Author : Joanne Whitehead; Rolf Ohlsson; Andras Paldi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : Genetic information is encoded by the linear sequence of the DNA double helix, while epigenetic information is overlayed as the packaging of DNA and associated proteins into the chromatin structure. Variations in chromatin structure play a vital role in establishing and maintaining patterns of gene expression during differentiation and development of higher eukaryotes, and disruption of this epigenetic gene regulation can lead to cancer. READ MORE

  4. 2. Dynamics and Mechanisms of Adaptive Evolution in Bacteria

    Author : Song Sun; Dan Andersson; Diarmaid Hughes; Josep Casadesús; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; adaptive evolution; mutation; genome rearrangements; antibiotic resistance; gene amplification; genome reduction; directed evolution; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Determining the properties of mutations is fundamental to understanding the mechanisms of adaptive evolution. The major goal of this thesis is to investigate the mechanisms of bacterial adaptation to new environments using experimental evolution. READ MORE

  5. 3. Library Preparation for High Throughput DNA Sequencing

    Author : Anders Jemt; Joakim Lundeberg; Petri Auvinen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; RNA; sequencing; massively parallel sequencing; library preparation; automation; genome; transcriptome; Bioteknologi; Biotechnology;

    Abstract : Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the genome. Before the introduction of massively parallel sequencing a little more than a decade ago it would cost around $10 million to get this blueprint. READ MORE

  6. 4. Cyanobacteria in symbiosis with boreal forest feathermosses : from genome evolution and gene regulation to impact on the ecosystem

    Author : Denis Warshan; Ulla Rasmussen; Elke Dittmann; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; Feathermosses; Symbiosis; Boreal forest; Gene flow; Proteogenomic; Transcriptomic; Community structure and composition; Dinitrogen fixation; Plant Physiology; växtfysiologi;

    Abstract : Among dinitrogen (N2)-fixing some cyanobacteria can establish symbiosis with a broad range of host plants from all plant lineages including bryophytes, ferns, gymnosperms, and angiosperms. In the boreal forests, the symbiosis between epiphytic cyanobacteria and feathermosses Hylocomium splendens and Pleurozium schreberi is ecologically important. READ MORE

  7. 5. Statistical methods for the detection and analyses of structural variants in the human genome

    Author : Shu Mei Teo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Structural variations (SVs) are an important and abundant source of variation in the human genome, encompassing a greater proportion of the genome as compared to single nucleotide polymorphisms (SNPs). This thesis investigates different aspects of SV analysis, focusing on copy number variations (CNVs) and regions of homozygosity (ROHs). READ MORE