Search for dissertations about: "[11C]Carbon monoxide"

Showing result 1 - 5 of 12 swedish dissertations containing the words [11C]Carbon monoxide.

  1. 1. Design and Synthesis of 11C-Labelled Compound Libraries for the Molecular Imaging of EGFr, VEGFr-2, AT1 and AT2 Receptors Transition-Metal Mediated Carbonylations Using [11C]Carbon Monoxide

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ola Åberg; Uppsala universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; [11C]carbon monoxide; isotopic labelling; PET; acrylamide; EGFR; VEGFR-2; 11C; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; Organisk kemi; Organic Chemistry; Organisk farmaceutisk kemi; Organic Pharmaceutical Chemistry;

    Abstract : This work deals with radiochemistry and new approaches to develop novel PET tracers labelled with the radionuclide 11C.Two methods for the synthesis of 11C-labelled acrylamides have been explored. READ MORE

  2. 2. Photoinitiated Radical Carbonylation Using [11C]Carbon Monoxide 11C-Labelling of Aliphatic Carboxylic Acids, Esters, and Amides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Oleksiy Itsenko; Uppsala universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; 11C-labelling; radicals; carbonylation; carbon monoxide; solvent effects; sensitizers; sulfoxides; WAY-100635; PET; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : One-step photoinitiated free radical carbonylation was employed for the rapid (5–7 min) labelling of aliphatic carboxylic acids, esters, and amides with a short-lived positron emitter 11C (t½ = 20.3 min) at the carbonyl position. The labelled compounds were synthesized from alkyl iodides (0.05–0. READ MORE

  3. 3. [11C]Carbon Monoxide and Aryl Triflates in Palladium-Mediated Carbonylation Reactions Synthetic approaches to [11C]Carbonyl Compounds and [11C]Amines

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Obaidur Rahman; Uppsala universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; [11C]Carbon monoxide; Aryl triflates; Carbonylation; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : The usefulness of low concentrations (typically 10 to 100 µM) of [11C]carbon monoxide and aryl triflates as substrates in 11C-carbonylation using different nucleophiles in the presence of lithium bromide was investigated. The reactions were performed in a micro autoclave of 200 µL volume and catalysed (mediated) by palladium(0). READ MORE

  4. 4. [11C]Carbon Monoxide in Rhodium-/Palladium-Mediated Carbonylation Reactions

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Julien Barletta; Uppsala universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; carbonylation reaction; carbon monoxide; PET; 11C-labelling; rhodium; palladium; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : Methods for the 11C-labeling of carbonyl compounds applicable in the preparation of radiotracers for Positron Emission Tomography (PET) are described. To this end [11C]carbon monoxide at low concentration was used in transition metal- mediated reactions. READ MORE

  5. 5. [11C]Carbon Monoxide in Palladium- / Selenium-Promoted Carbonylation Reactions Synthesis of 11C-Imides, Hydrazides, Amides, Carboxylic Acids, Carboxylic Esters, Carbothioates, Ketones and Carbamoyl Compounds

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Farhad Karimi; Uppsala universitet.; [2002]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : [11C]Carbon monoxide in low concentrations has been used in palladium- or seleniummediated carbonylation reactions such as the synthesis of 11C-imides, hydrazides, amides, carboxylic acids, esters, carbothioates, ketones and carbamoyl compounds.In these reactions aryl iodides have been used in most cases. READ MORE