Search for dissertations about: "[11C]raclopride"

Showing result 1 - 5 of 19 swedish dissertations containing the word [11C]raclopride.

  1. 1. Aerobic fitness and healthy brain aging : cognition, brain structure, and dopamine

    Author : Lars Jonasson; Carl-Johan Boraxbekk; Katrine Riklund; Emrah Düzel; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aerobic exercise; VO2; working memory; executive function; freesurfer; striatum; dopamine; D2-receptors; [11C]raclopride;

    Abstract : Background: Performing aerobic exercise and maintaining high levels of aerobic fitness may have positive effects on both brain structure and function in older adults. Despite decades of research however, there is still a rather poor understanding of the neurocognitive mechanisms explaining the positive effects of aerobic exercise on cognition. READ MORE

  2. 2. The longitudinal biology of depression : PET studies of the dopamine and serotonin systems

    Author : Jonas Svensson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The involvement of monoamine neurotransmission in the pathophysiology of depression was established already in the 1960s. However despite an abundance of research, the exact role of the serotonin (5-HT) and dopamine systems in depression have remained elusive. READ MORE

  3. 3. Assessment of dopamine and serotonin release in the non-human primate brain using PET

    Author : Sjoerd J. Finnema; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The molecular imaging technique positron emission tomography (PET) allows for non-invasive examination of biochemical markers in the living brain. For over three decades PET studies have provided important insight into the relationship of monoaminergic neurotransmitter systems to brain functioning and psychiatric disorders. READ MORE

  4. 4. Catecholaminergic neurotransmission in heart and brain : development of tracers for positron emission tomography

    Author : Claus Oliver Langer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : PET; Radioligand; Catecholamine; Norepinephrine; Dopamine; Heart; Brain; Metaraminol; Dopamine D2 Receptor;

    Abstract : The catecholamines norepinephrine and its biosynthetic precursor dopamine are two principal neurotransmitters in the human central nervous system (CNS). Moreover, norepinephrine is a major transmitter substance in the peripheral, autonomic nervous system. READ MORE

  5. 5. Assessment of Graft Effects and Function in Cell Replacement Therapy for Parkinson's Disease

    Author : Peter Hagell; Äldres hälsa och personcentrerad vård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; neuropsychology; Neurology; measurement; psychometrics; perceived health; dyskinesias; assessment; striatum; positron emission tomography; dopamine; Parkinson s disease; transplantation;

    Abstract : This explorative study aimed to apply, develop, and evaluate assessment methods at various levels in cell replacement therapy for Parkinson’s disease (PD). Observed motor effects in five grafted patients support that timed motor tasks and clinical ratings of parkinsonism are able to monitor motor function, but their psychometric properties need further attention. READ MORE