Search for dissertations about: "Åsa Hagner-McWhirter"

Found 1 swedish dissertation containing the words Åsa Hagner-McWhirter.

2. 1. Glucuronyl C5-epimerases in the biosynthesis of glycosaminoglycans

   Author : Åsa Hagner McWhirter; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

   Abstract : This thesis is focused on two enzymes, both glucuronyl CS-epimerases, that catalyse the conversion of D-glucuronic acid (GlcA) into L-iduronic acid (IdoA) residues in the repeating disaccharide units of heparin/heparan sulphate (HS) and dermatan sulphate (DS) polymers. These glycosaminoglycans are produced as proteoglycans, in which linear polysaccharide chains are attached covalently to a protein core. READ MORE