Search for dissertations about: "Åsa Wallén-mackenzie"

Showing result 1 - 5 of 8 swedish dissertations containing the words Åsa Wallén-mackenzie.

  2. 1. United in Diversity : A Physiological and Molecular Characterization of Subpopulations in the Basal Ganglia Circuitry

    Author : Thomas Viereckel; Åsa Wallén-Mackenzie; Åsa Konradsson-Geuken; Erika Comasco; Per Svenningsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Glutamate; Optogenetics; Amperometry; Histology; Midbrain; Subthalamic Nucleus; Parkinson s disease; Ventral Tegmental Area; Substantia Nigra; Co-release;

    Abstract : The Basal Ganglia consist of a number of different nuclei that form a diverse circuitry of GABAergic, dopaminergic and glutamatergic neurons. This complex network is further organized in subcircuits that govern limbic and motor functions in humans and other vertebrates. READ MORE

  4. 2. Motion and Emotion : Functional In Vivo Analyses of the Mouse Basal Ganglia

    Author : Emma Arvidsson; Åsa Wallén-Mackenzie; Cecilia Flores; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine; Basal Ganglia; Reward System; In Vivo Chronoamperometry; Optogenetics; Deep Brain Stimulation; Parkinson’s Disease; Addiction; Glutamate; Vesicular Glutamate Transporter; VGLUT2; Sex; Age; Subthalamic Nucleus; Striatum; Nucleus Accumbens; Ventral Tegmental Area;

    Abstract : A major challenge in the field of neuroscience is to link behavior with specific neuronal circuitries and cellular events. One way of facing this challenge is to identify unique cellular markers and thus have the ability to, through various mouse genetics tools, mimic, manipulate and control various aspects of neuronal activity to decipher their correlation to behavior. READ MORE

  5. 3. The subthalamic nucleus in motor and affective functions : An optogenetic in vivo-investigation

    Author : Adriane Guillaumin; Åsa Wallén-Mackenzie; Konstantinos Meletis; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Subthalamic nucleus; optogenetics; basal ganglia; locomotion; Parkinson s disease; aversion; Neuroscience; Neurovetenskap;

    Abstract : The basal ganglia form a group of subcortical interconnected nuclei involved in motor, limbic and cognitive functions. According to the classical model of the basal ganglia, two main pathways exert opposing control over movement, one facilitating movement and the other suppressing movement. READ MORE

  6. 4. Neuronal Networks of Movement : Slc10a4 as a Modulator & Dmrt3 as a Gait-keeper

    Author : Martin Larhammar; Klas Kullander; Leif Andersson; Åsa Wallén-Mackenzie; Robert Fyffe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synaptic vesicle transporter; Neuromodulation; Dopamine; Central Pattern Generator; Locomotion; Gait; Horse; Mouse; Commissural Inhibitory Interneuron; Neuroscience; Neurovetenskap;

    Abstract : Nerve cells are organized into complex networks that comprise the building blocks of our nervous system. Neurons communicate by transmitting messenger molecules released from synaptic vesicles. Alterations in neuronal circuitry and synaptic signaling contribute to a wide range of neurological conditions, often with consequences for movement. READ MORE

  7. 5. Functional Analysis of the Vesicular Glutamate Transporter 2 in Specific Neuronal Circuits of the Brain

    Author : Karin Nordenankar; Åsa Wallén-Mackenzie; Rainer Spanagel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Addiction; amphetamine; affective behaviour; cocaine; cognitive behaviour; conditional knockout mouse; dopamine; operant self-administration; reward system; schizophrenia; Neuroscience; Neurovetenskap;

    Abstract : A key issue in neuroscience is to determine the connection between neuronal circuits and behaviour. In the adult brain, all neuronal circuits include a glutamatergic component. READ MORE