Search for dissertations about: "â-cell."

Showing result 21 - 25 of 558 swedish dissertations containing the word â-cell..

  2. 21. Gene expression and its physiological control in disease and development : Studies on the human PDGF-B gene and tumour hypoxia

    Author : Erik Ullerås; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Zoologisk utvecklingsbiologi; Animal Development;

    Abstract : Strict control of gene expression is essential during development and in response to physiological stimuli. This thesis describes the functional characterisation of the gene regulatory mechanisms controlling the expression of the potent human growth factor Platelet Derived Growth Factor B gene, in a cell type specific context and in response to low oxygen tension. READ MORE

  4. 22. Functional studies of calcein acetoxymethyl ester in human tumor cells

    Author : Gunnar Liminga; Uppsala universitet; []
    Keywords : Medical sciences; Calcein AM; Calcein; Functional assay; Drug resistance; Cytotoxicity; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; klinisk farmakologi; Clinical Pharmacology;

    Abstract : A fluorometric assay for functional measurement of P-glycoprotein 170 (Pgp) mediated transport in cell lines, using the acetoxymethyl ester of calcein (calcein/AM) as a probe was established. The myeloma cell line RPMI 8226/S and the two Pgp-expressing doxorubicin resistant subcell lines 8226/dox6 (low) and 8226/dox40 (high) were used. READ MORE

  5. 23. Toward a tissue engineered blood vessel. Cell cultivation, hemodynamic influences and matrix production

    Author : Sepideh Heydarkhan-Hagvall; Göteborgs universitet; []
    Keywords : tissue engineered blood vessel; co-culture vascular cells; angiogenic factors; ; hemodynamic; extracellular matrix; stem cells;

    Abstract : Cardiovascular diseases are the leading causes of mortality in the western world. Thereplacement or repair of diseased blood vessels with human autografts (vein or arteries) orsynthetic vascular grafts (ePTFE or Dacron) has become a routine treatment. Autologous graftsare not always available in all patients. READ MORE

  6. 24. Peptidoglycan regulation of Drosophila immunity

    Author : Jenny Karlsson; Håkan Steiner; Kenneth Söderhäll; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; molekylärgenetik; Molecular Genetics;

    Abstract : Innate immunity is an ancient defense system that distinguishes between self and non self and is present in both vertebrates and invertebrates. Peptidoglycan (PGN), a cell wall component shared by both gram-negative and gram-positive bacteria, is the major recognition molecule for the detection of bacteria in Drosophila. READ MORE

  7. 25. Cell cycle regulation and DNA damage response : a record of polo-like kinase 1 activity

    Author : Elvira Hukasova; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Division and cell proliferation is an essence of life. A human cell has in its core a very simple yet a very complex machinery to coordinate cell cycle activities and events. READ MORE