Search for dissertations about: "â-cell."

Showing result 6 - 10 of 558 swedish dissertations containing the word â-cell..

  2. 6. Regulation of intracellular signaling events that modulate insulin action

    Author : Silvia Gogg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; insulin resistance; EGF; Gab 1; insulin receptor substrate; PI3-kinase; ; Thiazolidinediones; PPARã; insulin signaling; glucose transport; adipose tissue; â-cell.;

    Abstract : Insulin regulates several mechanisms of fundamental importance to the body involving glucose, fat andprotein metabolism. Insulin resistance in skeletal muscle, liver and adipose tissue promotes an increaseddemand for insulin secretion. READ MORE

  4. 7. Salt-inducible kinase 1 : a novel regulator within a cell sodium-sensing network

    Author : Karin Stenström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Na ; K -ATPase; -adducin; Milan hypertensive and normotensive strain of rats; hypertension; angiotensin II; cardiac hypertrophy; myocyte enhancer factor-2 and nuclear factor of activated T-cells;

    Abstract : Na+, K+-ATPase (NK) is expressed in all animal cells and plays a crucial role in cellular ion homeostasis. The NK activity is tightly regulated by specific signaling networks that must be well controlled in time and space (at the plasma membrane or in the intracellular compartments) to guarantee the specificity of the physiological response. READ MORE

  5. 8. Exploring Yeast as a Cell Factory for the Production of Carboxylic Acids and Derivatives

    Author : Diogo Portugal-Nunes; Teknisk mikrobiologi; []
    Keywords : Saccharomyces cerevisiae; Poly-3-D-hydroxybutyrate PHB ; Carboxylic acids; Alpha-ketoglutarate AKG ; Xylose assimilation; Weimberg pathway;

    Abstract : Baker’s yeast, Saccharomyces cerevisiae, is a promising cell factory for the sustainable utilization of renewable resources for the formation of products with commercial value. Among these, poly-3-D-hydroxybutyrate (PHB) is an extensively studied biopolymer naturally accumulated in some bacteria and archaea species through the formation of carbon granules. READ MORE

  6. 9. Signal transduction via ion fluxes : a cell imaging study with emphasis on calcium oscillations

    Author : Per Uhlén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Calcium; Ca2 signalling; Ca2 oscillation; InsP3; InsP3 receptor; Na; K-ATPase; ouabain; physical interaction; FRET; spectral analysis; confocal microscopy;

    Abstract : Signal transduction via ion fluxes is of vital importance for all mammalian cells. Cells can exploit ion regulatory mechanisms to generate and transmit intracellular signals. Improvements in digital microscopic imaging technology have made it possible to explore micro-environments and complex intracellular machineries. READ MORE

  7. 10. Saliva: a cell suspension of epithelial cells harboring the antimicrobial peptide LL-37 and the growth factor EGF

    Author : Alexandra Aidoukovitch; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Saliva; Oral health; Innate immunity; Cathelicidin; LL-37; Host defense peptides; EGF; Saliva; Oral health; Innate immunity; Cathelicidin; LL-37; Host defence peptides; EGF;

    Abstract : Saliva plays a crucial role in maintaining oral health through its physical and chemical properties that provide various protective functions. One of its essential components is the human host defense peptide LL-37, which is produced by immune cells and epithelial cells, and participates in the first line of defense against pathogens. READ MORE